65,437 trials
Plaque Psoriasis
Primary: Percentage of Participants Who Achieved a Psoriasis Area and Severity Index (PASI) 75 Response at Week 16 — 32.4; 43.6; 57.9 percentage of participants — p=0.027
Pulmonary Tuberculosis
Primary: Early Bactericidal Activity (EBA) Measured as the Daily Rate of Change in log10 CFUs (Colony Forming Units) of M. Tuberculosis in Sputum on Solid Media (Days 0-14)…
Psoriasis
Primary: Change From Baseline in the Palmo-plantar Pustulosis Psoriasis Area and Severity Index (PPPASI) Score at the End of Treatment (EOT) (Week 24) or at the Last Assessment…
Low Back Pain
Primary: Change From Baseline in Oswestry Disability Scale (0-100%) — -8.26; -7.75; -8.00; -9.48 units on a scale
Chronic Pain · Low Back Pain · Analgesia
Primary: Change in Weekly Average Electronic Diary (eDiary) Numeric Rating Scale -Pain (NRS-Pain) Score From Randomization Baseline to Final 2 Weeks (Average of Weeks 11 and 12)…
Healthy Subjects
Primary: Change in Whole Lung Mucociliary Clearance — 0.6; -4.0 % Clearance — p=<.05
Breast Cancer · Hot Flashes · Menopausal Symptoms
Primary: To Evaluate the Efficacy of Flaxseed on Hot Flash Scores in Women as Measured by a Daily Prospective Hot Flash Diary. — -4.9; -3.5 units on a scale — p=0.29
Gastroesophageal Reflux Disease
Primary: Patients Requiring Endoscopic Removal of BRAVO Because of Reported Discomfort — 2; 0 participants
Non-emergent, Abdominal or Thoracic Procedures
Primary: The Primary Endpoint is the Incidence of Reported Device-related Adverse Events (AEs) Through 30 Days Following Indicated Abdominal or Thoracic Procedures. — 2; 1 Device…
Central Neuropathic Pain · Allodynia · Spinal Cord Injury
Primary: Mean Pain Intensity (Percent Change From Baseline) — -0.006; -0.018; -0.073; -0.24 Percent change from baseline
Stroke
Primary: Percent Change From Baseline in Jebsen Taylor Hand Function Test Scores — -23.0; 0 percentage of change from baseline
Leukemia, Myeloid, Acute
Primary: Phase I: Maximum Tolerated Dose of Plerixafor Plus G-CSF When Combined With MEC — 750 mcg/kg/day
Carcinoma of Unknown Primary
Primary: Confirmed Response Rate (Partial or Complete Response for 2 Consecutive Evaluations at Least 4 Weeks Apart) as Measured by RECIST Criteria — 9; 13 percentage of patients…
Type 2 Diabetes Mellitus
Primary: Change in HbA1c From Baseline to End — -0.54 HbA1c in percent — p=<0.02
Breast Cancer
Primary: Six-month Progression-free Survival (PFS) Rate at 6 Months — 39 percentage of patients