Phase 4 N=60 Thrombectomy REvascularization of Large Vessel Occlusions in Acute Ischemic Stroke (TREVO)
Ischemic Stroke
Primary: Revascularization Status — 92 percentage of subjects TICI 2 or >
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=104 An Efficacy and Tolerability Study of TRAVATAN® Versus LUMIGAN®
Glaucoma · Ocular Hypertension
Primary: Mean Change From Baseline in Intraocular Pressure (IOP) at Month 6 — 24.66; 24.59; -7.61; -7.35 mmHg
Phase 4 N=261 A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate Versus RoActemra/Actemra Monotherapy in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate
Rheumatoid Arthritis
Primary: Change in Disease Activity Score Based on 28-Joint Count (DAS28) From Week 16 to Week 28 — 5.42; 5.29; 1.77; 1.96 units on a scale — p=0.700
Phase 4 N=27 A Study of VIVITROL in the Prevention of Re-arrest and Re-incarceration
Opioid Dependence
Primary: Incidence of Subject Re-arrest — 6; 2 participants re-arrested — p=>0.05
Phase 4 N=35 True Functional Restoration and Analgesia in Non-Radicular Low Back Pain
Low Back Pain
Primary: Change in McGill Pain Questionnaire - Short Form — -0.73; -3.78 units on a scale
Phase 4 N=2,199 A Chronic Care Model Based Quality Improvement (QI) Program to Improve the Care of Patients With Chronic Kidney Disease (CKD)
Chronic Kidney Disease
Primary: Systolic Blood Pressure (SBP) — 135.1; 134.4 mmHg — p=0.57
Phase 4 N=96 The Feasibility of Florbetapir Quantitation in Europe
Alzheimer's Disease
Primary: Change in Reader Accuracy After Application of Quantitation Software — 0.0746 Net Reclassification Index — p=0.0001
Phase 4 N=79 Investigate the Impact of Early Treatment Initiation With Tiotropium in Patients Recovering From Hospitalization for an Acute COPD Exacerbation 1
Pulmonary Disease, Chronic Obstructive
Primary: Change From Baseline of Trough FEV1 at 12 Weeks on Study Drug — -0.051; 0.183 Litres
Phase 4 N=161 Investigating Efficacy and Safety of Biphasic Insulin Aspart 50 Twice Daily Versus Biphasic Human Insulin 50 Twice Daily Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes Mellitus
Diabetes · Diabetes Mellitus, Type 2
Primary: 2-hour PPG (Postprandial Plasma Glucose) Increment Following a Standard Meal Test — 5.30; 6.41 mmol/L — p=< 0.001
Phase 4 N=249 Daptomycin Versus Vancomycin in Participants With Skin Infections Due to MRSA
Staphylococcal Skin Infections
Primary: Infection-Related Hospital Length of Stay — 91.46; 93.23 Hours
Phase 4 N=525 An Effectiveness Trial of Maintenance Therapy for Nicotine Dependence
Nicotine Dependence
Primary: Point Prevalence Abstinence — 84; 35 participants
Phase 4 N=602 Prophylactic Ephedrine and Combined Spinal Epidurals for Labor
Labor Pain
Primary: Early Profound Fetal Bradycardia — 8; 14 participants — p=0.18
Phase 4 N=40 Efavirenz Versus Rilpivirine on Vascular Function, Inflammation, and Oxidative Stress
Cardiovascular Disease
Primary: Change in Flow-mediated Dilation of the Brachial Artery — 0.089; 0.63 absolute percentage change — p=0.30
Phase 4 N=27 The Effect on Depressive Symptoms in ECF Residents With COPD
Chronic Obstructive Pulmonary Disease · Depression
Primary: To Determine the Effect of Treating COPD Patients With Advair Diskus for 16 Weeks on the Cornell Depression Scale or Section D SUM of the Minimum Data Set 3.0 — 8.7…
Phase 4 N=280 A Study of Alvimopan for the Management of Postoperative Ileus in Participants Undergoing Radical Cystectomy
Postoperative Ileus
Primary: Mean Time to Achieve GI2 Analyzed by Kaplan-Meier (KM) Estimates and Cox Proportional Hazards (PH) Model — 164.2; 132.7 Hours — p=<0.0001