65,437 trials
Depression, Unipolar
Primary: Intent-to-Treat Analysis of Adjusted Mean Beck Depression Inventory-II Scores Over Intervention Period — 20.98; 19.92; 15.15; 13.06 points on a scale — p=0.034
Cataract
Primary: Distance Corrected Intermediate Visual Acuity — 0.105; 0.343 LogMAR
Non-Germinal B-Cell-like (GCB) Diffuse Large B-cell Lymphoma (DLBCL)
Primary: Progression-Free Survival (PFS) in Patients With Non-germinal Center B-cell-like (Non-GCB) Diffuse Large B-cell Lymphoma (DLBCL) — NA; NA months
Ulcer · Venous Ulcer · Skin Ulcer
Primary: Logarithm of Percentage of Baseline Ulcer Size — 3.6043; 3.5030 Mean of log (percentage of baseline area — p=0.652
Hepatitis C
Primary: Primary: Percentage of Participants Achieving Sustained Virologic Response at 12 Weeks After the End of All Treatment (SVR12) — 99.2; 90.5 percentage of participants…
Osteoarthritis
Primary: Presence of Osteolysis — 2; 2 Hips
Bioequivalence · Healthy Japanese Subjects · Pharmacokinetics
Primary: Maximum Observed Plasma Concentration (Cmax) of Ticagrelor and Its Active Metabolite AR-C124910XX. — 529; 534; 569; 165 ng/mL
Juvenile Idiopathic Arthritis
Primary: Percentage of Participants Experiencing a American College of Rheumatology (ACR) Pediatric 30 Response at Week 16 — 90.0 percentage of participants
Healthy Volunteers
Primary: Ceftriaxone PK Maximum Observed Plasma Concentration (Cmax) With (Period 2) and Without (Period 1) SYN-004. — 137,800.0; 178,600.0; 143,800.0; 169,200.0 ng/mL
Urology
Primary: Usability Factors; Simple, Doable, and is Comparable to the Ruler-based Manometry Method Using a Questionnaire and Patient Diary. — 65 participants
Brain and Central Nervous System Tumors
Primary: Maximum Tolerated Dose (MTD) of Everolimus (RAD001) in Combination With Temozolomide (TMZ) and 3D-conformal Radiotherapy (RT) or Intensity-modulated Radiotherapy (IMRT)…
Multiple Myeloma
Primary: Number of Participants With Grade 3 or Grade 4 (G3/4) Infusion Reactions by the End of Treatment Cycle 2 — 0 Participants
Gestational Hypertension
Primary: Pregnancy Loss or NICU Admission for Greater Than 48 Hours — 155; 150 participants
Thrombosis
Primary: Incidence of Arterial Bleeding — 1 Participants
Health Literacy · Health Insurance · Health Services Accessibility
Primary: Knowledge Score (% Correct) — 77.6; 58.8 percentage of 8 items correctly answered — p=<.001