65,437 trials
Diverticulosis, Colonic · Rectal Neoplasms · Colonic Neoplasms
Primary: Concentration of Ertapenem in Colorectal Tissue in mg/kg 3 to 6 Hours After a Single Dose of 1 Gram Ertapenem I.V..
Methamphetamine Dependence
Primary: Time Till Relapse — 7; -8 Days to Relapse — p=<0.05
Smoking
Primary: Airway Blood Flow — 2.13; 13.05 ΔQaw (ul/min/ml)
Depression
Primary: Depressive Symptoms — 12.5; 13.4; 7; 5.2 units on a scale — p=0.42
Diabetes Mellitus, Type 2
Primary: Absolute Change From Baseline in Glycosylated Hemoglobin (HbA1c) at Week 24 — -0.38; -0.87; -0.75 percentage of hemoglobin — p=<0.0001
Type 2 Diabetes Mellitus
Primary: Change in HbA1c From Baseline — -0.97; 0.13 Percent — p=<0.001
Clostridium Difficile Infection
Primary: Percentage of Participants With Clostridium Difficile Infection (CDI) Recurrence — 25.9; 17.4; 15.9; 27.6 Percentage of participants — p=0.3182
Age-related Macular Degeneration · Choroidal Neovascularization
Primary: Change in Best Corrected Visual Acuity (BCVA) From Baseline to Month 12 — 6.2; 8.1 Letters (EDTRS) — p=<0.001
Acute Lung Injury · Acute Respiratory Distress Syndrome
Primary: Number of Participants Receiving Mechanical Ventilation — 51; NA participants
Asthma
Primary: Number of Participants Experiencing an Event in the Composite Endpoint (Asthma-related Death, Asthma-related Intubation or Asthma-related Hospitalization) — 43; 40…
Acute Myocardial Infarction · Pacing Therapy · Cardiac Remodeling
Primary: Change in Left Ventricular End Diastolic Volume (LVEDV) — 16.4; 15.8 mL
Malignant Melanoma, Neoplasms
Primary: Area Under the Plasma Concentration Time-curve From Zero to the Last Measurable Concentration Time Point (AUClast) of Vemurafenib — 125; 76.7 mcg*h/mL
Chronic Venous Insufficiency
Primary: Ease of Use and Comfort for Subjects Using the ACTitouch System. — 70.8; 37.5; 89.2; 59.4 Percent of participants
Rheumatoid Arthritis
Primary: Change From Baseline in Clinical Disease Activity Index (CDAI) at Week 24 — -21.6 units on a scale — p=<0.0001
Alpha 1-Antitrypsin Deficiency
Primary: Adverse Events Possibly, Probably or Definitely Related to Study Drug — 2; 2; 3; 2 participants