65,437 trials
Bone Fracture · Radius Fracture · Ankle Fracture
Primary: Efficient Casting With Woodcast Circular System — 90 participants
Breast Neoplasms
Primary: Percentage of Participants With Disease Free Survival at 5 Years — 75.5; 83.2; 81.0 percentage of participants
Focal Epilepsy With and Without Secondary Generalization
Primary: The Percent Change in Ratio of Dose and Defined Daily Dose (DDD) for the Drug Load of Concomitant Anti-Epileptic Drugs (AEDs) From Baseline to the End of Observation…
Post Operative Pain
Primary: Median Pain Score During Shift 1, as Measured With the Face, Legs, Activity, Cry, Consolability Scale — 1.0; 1.8; 1.5 units on a scale
Adult Anaplastic Astrocytoma · Adult Anaplastic Oligodendroglioma · Adult Giant Cell Glioblastoma
Primary: Number of Participants With Dose-limiting Toxicities Due to Romidepsin Graded According to the NCI Common Toxicity Criteria (CTCAE Version 3.0) (Phase I) — 0 participants
Chronic Obstructive Pulmonary Disease
Primary: Change From Baseline in Normalized Forced Expiratory Volume in 1 Second (FEV1) Area Under the Curve Over 12 Hours (AUC0-12h) After Morning Study Drug Administration at…
Hepatitis C Virus Infection
Primary: Percentage of Participants With Sustained Virologic Response (SVR) 12 Weeks After Discontinuation of Therapy (SVR12) — 99.3; 93.9 percentage of participants — p=0.018
Atopic Dermatitis (AD)
Primary: Percentage With Erythema on the Face at Baseline Before Investigational Product Application — 33.3; 71.9; 55.6; 6.3 Percentage of participants
Prostate Cancer
Primary: Gene Expression of Phase II Enzymes — -0.36; 0.26; 0.15; -0.59 -fold change in expression
Lymphoceles · Prostate Cancer
Primary: Incidence of Lymphoceles — 10; 12; 104; 102 participants — p=0.412
Oral Lichen Planus
Primary: Pain — 0; 4; 4.4 units on a scale
Menorrhagia
Primary: Menstrual Blood Loss (MBL) as Measured by Pictorial Blood Loss Assessment Chart (PBLAC). — 15; 0 units on a scale — p=0.003
Esophageal Cancer
Primary: Response Rate (RR) — 6 percentage of participants
Chronic Venous Insufficiency
Primary: Mean Change (Reduction) From Baseline in Volume of Reference Leg at Week 16 — 1.13; 5.78 milliliters (mL) — p=0.531
Breast Augmentation · Breast Reconstruction · Breast Revision
Primary: 6-Year Kaplan-Meier Estimated Cumulative Incidence Rate of Occurrence of Any Reoperation — 8.3; 31.7; 13.8; 31.3 percentage of subjects