Phase 2 N=11 Antineoplaston Therapy in Treating Children With Low-Grade Astrocytoma
Low Grade Astrocytomas
Primary: Number of Participants With Objective Response — 4; 1; 4; 0 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=455 Efficacy and Safety of Ranibizumab With or Without Laser in Comparison to Laser in Branch Retinal Vein Occlusion
Branch Retinal Vein Occlusion
Primary: Mean Change in Visual Acuity: BCVA Change at Month 6 Compared to Baseline in Patients With Visual Impairment Due to Branch Retinal Vein Occlusion (BRVO) — 59.5; 56.6…
N/A N=63 Real-Time Antiretroviral Therapy Adherence Intervention in Uganda
HIV/AIDS · Adherence
Primary: Antiretroviral Therapy (ART) Adherence Levels — 91; 79; 79 Percent adherence — p=<0.05
Phase 4 N=406 Evaluating the Control of COPD Symptoms in Patients Treated With Tiotropium Bromide 18mcg Once Daily Alone, ADOAIR 50/250mcg Twice Daily Alone or ADOAIR 50/250mcg Plus Tiotropium Bromide 18mcg
Pulmonary Disease, Chronic Obstructive
Primary: Percentage of Participants Who Were Able to Remain on the Randomized Treatment — 62.69; 66.67 Percentage of participants
N/A N=899 Pioglitazone Tablets Special Drug Use Surveillance "Combined Use of Biguanides / Long-term Treatment"
Type 2 Diabetes Mellitus
Primary: Number of Participants Reporting One or More Adverse Drug Reactions — 79 participants
Phase 4 N=278 Different LD of Ticagrelor for Antiplatelet Effect in Patients With Non-ST-segment Elevation ACS Undergoing PCI
Non ST Segment Elevation Acute Coronary Syndrome
Primary: Platelet Reactivity Index(PRI) Measured by VASP-P — 16.7; 12.2 percentage of 100
N/A N=7 Role of Glucagon-Like Peptide-1 in Postprandial Hypoglycemia
Postprandial Hypoglycemia
Primary: Mean Plasma Glucose Area Under the Curve (AUC 0-3h) — 22,192.5; 25,207.1; 21,715.9 mg*min/dl
Phase 2 N=70 A Study of Alpharadin With Docetaxel in Patients With Bone Metastasis From Castration-Resistant Prostate Cancer (CRPC)
Bone Metastases · Castration-Resistant Prostate Cancer
Primary: Number of Subjects With Dose-Limiting Toxicities - Dose Escalation Part — 0; 0; 0 Participants
Phase 4 N=12 Post-treatment Effects of Ivermectin (IVM) or Diethylcarbamazine (DEC) in Loiasis
Loiasis
Primary: The Peak % of Baseline Eosinophil Count Measured During the First 7 Days Post-treatment. — 196; 165 percentage of baseline — p=0.68
Phase 2 N=33 Efficacy and Safety of Olaparib in Pretreated Patients With Measurable Colorectal Cancer, Stratified by Microsatellite Instability (MSI) Status
Colorectal Cancer
Primary: Tumour Response — 0; 0 Percentage of Participants
Phase 4 N=2,004 Brilinta DaYu Study
Acute Coronary Syndrome
Primary: Bleeding Events — 17; 27; 93; 426 Participants
Phase 2 N=60 A Study of Capecitabine Plus Oxaliplatin in Combination With Pre-operative Pelvic Radiotherapy in Rectal Cancer
Rectal Cancer
Primary: Percentage of Participants With Pathological Complete Tumor Response — 23 Percentage of participants
Phase 2 N=9 Effect of Exendin-(9-39) on Glycemic Control in Subjects With Congenital Hyperinsulinism
Congenital Hyperinsulinism
Primary: Mean Blood Glucose Area Under the Curve (AUC 0-6h) — 2,096; 1,678 mmol*min/L
N/A N=548 Clinical Study of Approved and Investigational Contact Lenses
Visual Acuity
Primary: Subjective Overall Comfort Composite Score — 65.17; 68.58; 66.45; 65.46 average clue score
Phase 4 N=30 A Double-blind, Placebo-controlled, Crossover Study to Assess the Effect of Aclidinium Bromide 400 μg Bid on COPD Symptoms and Sleep Quality After 3 Weeks of Treatment in Patients With Stable Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease (COPD)
Primary: Change From Baseline in Normalized Forced Expiratory Volume in One Second (FEV1) AUC0-24hr — 0.0953; -0.0429 L/sec*hr