65,437 trials
Chronic Obstructive Pulmonary Disease
Primary: Change From Baseline in Normalized Forced Expiratory Volume in One Second (FEV1) Area Under the Curve Over 12 Hours (AUC0-12) — 0.187; 0.189; 0.144; 0.114 Liters…
Chronic Heart Failure
Primary: Percentage of Participants With Chronic Heart Failure (CHF) Who Develop Anti-serelaxin Antibodies at Any Time Following Repeat Administration of IV Continuous Infusions…
Colorectal Cancer
Primary: Median Progression-free Survival (PFS) — 254 Days
Urolithiasis
Primary: Stone Free Rate — 81; 91; 98 Participants
Rheumatoid Arthritis
Primary: Change From Baseline to Week 4 in Synovitis of the Wrist According to Rheumatoid Arthritis Magnetic Resonance Imaging (RAMRIS) Score — 5.78; -0.88 units on a scale
ADHD
Primary: Parent-rated ADHD Symptoms — 20.5; 24.1 scores on a scale — p=<.05
HIV · HIV Infections
Primary: Number of Patients With Plasma HIV RNA < 50 Copies/mL — 105; 92; 97 participants
Painful Diabetic Neuropathy
Primary: Change From Baseline to Week 12 in the Average Daily Pain NPRS (Numeric Pain Rating Scale) Score; mLOCF Imputation — -1.9; -2.4; -1.5; -2.7 units on a scale — p=0.168
Psoriasis
Primary: The Number of Visits at Which Participants Achieved a Static Physician Global Assessment (PGA) Score of Cleared (0) or Minimal (1) — 4.5; 4.1 number of visits
Meningitis · Meningococcal Meningitis · Meningococcal Infections
Primary: Percentage of Participants With Meningococcal Antibody Titers ≥ 1:4 Before, 28 Days After, and Approximately Four Years Following Menactra Vaccine Booster Vaccination…
Leukemia
Primary: Participant Best Response Assessed Using Response Evaluation Criteria In Solid Tumors (RECIST) Version 1.1 — 0; 0; 1; 1 participants
Post-stroke Spasticity of the Lower Limb
Primary: Change From Baseline in Ashworth Scale (AS) for Plantar Flexors at Week 4 — 2.8; 2.8; -0.4; -0.4 Units on a scale — p=0.777
Alcohol Dependence
Primary: Alcohol Craving in Response to the Alcohol Cue Script — 11.6932; 14.6126 Units on a scale
Cervical Dystocia
Primary: Cervical Length Prior to Labor Induction — 2.9; 3 centimetres
Diabetes Mellitus, Type 2
Primary: Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs) — 2; 2; 1; 1 participants