65,437 trials
Migraine
Primary: Migraine Frequency at 12 Weeks — -5.5; -3.9 days
Diabetes · Diabetes Mellitus, Type 2
Primary: Change in HbA1c From Baseline — -1.27; -1.04 percentage change in HbA1c — p=<0.001
Hemorrhage
Primary: CBC Hemoglobin Measurement Compared to Non-invasive Radical-7 Measurement — 10.7; 9.2 grams per deciliter
Vitamin D Deficiency
Primary: 25-Hydroxyvitamin D Concentration — 32.5; 41.0; 45.7 ng/mL
Pulmonary Arterial Hypertension
Primary: Plasma Estradiol (E2) Level — -40; -4 % change from baseline
Hemophilia A
Primary: Treatment Success — 92.4; 92.2; 92.3 % bleeding events successfully treated
Pulmonary Disease, Chronic Obstructive
Primary: Number of Participants With Death (Both on and Off Treatment) Due to Any Cause, Time up to or on the Pre-determined Common End Date — 275; 251; 265; 246 Participants…
Obesity
Primary: Gastric Emptying Half-time (T 1/2) of Solids — 187; 86 minutes — p=<.001
Locally Recurrent · Metastatic Breast Cancer ( HER2 Negative)
Primary: Objective Response Rate (ORR) — 28.6 Percentage of participants
Lung Cancer
Primary: PERCIST Partial Metabolic Response — 6 participants
Influenza
Primary: Percentage of Participants Excreting Resistant Virus — 26.3; 35.3 percentage of participants — p=0.825
Non-small Cell Lung Cancer Stage III · Non-Small-Cell Lung Cancer Metastatic
Primary: Number of Patients With T790M Mutation Detected by Amplification Refractory Mutation System (ARMS) Assay — 97 participants
Chronic Kidney Disease
Primary: Factors That Are Most Important to Patients — 98; 93; 97; 100 % of patients
Total Knee Replacement Surgery
Primary: Time Weighted Average Verbal Response Scale Pain Score — 3.52; 3.24; 3.40 units on a scale — p=< 0.001
Rheumatoid Arthritis
Primary: Change From Baseline in Morning Stiffness Duration at Week 12 as Assessed by Patient Diary — -16.76 minutes