N/A N=1,236 A Test of Short and Long Term Naturalistic Outcomes of Smokers Who Sample Smokeless Tobacco
Smoking · Smoking Cessation
Primary: Quit Attempts and Abstinence — 25.7; 30.8; 19.8; 25.6 percentage of participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=65 A Study to Establish the Efficacy of QBX258 in Patients With Moderate to Severe Asthma
Asthma
Primary: Change From Baseline in Asthma Control Questionnaire (ACQ) Score — -0.513; 0.001 score on a scale — p=0.005
N/A N=4,455 Study to Evaluate Impact of School-based Influenza Vaccination on School Populations
Influenza
Primary: Rates of Confirmed Influenza Illness in Vaccinated and Non-vaccinated Children Attending Schools With and Without School-based Influenza Vaccination Programs — 58.0…
Phase 2 N=19 PK/PD Study With G-Pump (Glucagon Infusion) in T1DM Patients
Hypoglycemia
Primary: Time to Reach 50% of Maximum Glucose Concentration (Glucose T50%-Early) — 17.2; 21.9; 21.3; 7.6 minutes — p=0.23
Phase 2 N=20 Diabetic Macular Edema Treated With Ozurdex (DMEO)
Diabetic Macular Edema
Primary: Correlation Between Change in Level of Propermeability Factors With Change in Edema After Treatment With a Dexamethasone Implant or Anti-VEGF Agent — 0.47; 0.059; 0.45…
Phase 2 N=420 Safety and Immunogenicity of Norovirus GI.1/GII.4 Bivalent VLP Vaccine
Healthy Volunteers · Norovirus, Prevention
Primary: Percentage of Participants With a Seroresponse (Pan-Ig ELISA) — 43.3; 62.1; 46.4; 35.5 percentage of participants
N/A N=14 A P300 Brain Computer Interface to Operate Power Wheelchair Tilt
Healthy · Amyotrophic Lateral Sclerosis
Primary: The Accuracy of BCI Typing While Tilting in a Power Wheelchair and While Sitting Still in a Power Wheelchair. — 91.04; 91.18; 88.38 % Accuracy of selections
Phase 2 N=127 Phase II Safety and Efficacy Study of Crizotinib in East Asian Patients With ROS1 Positive, ALK Negative Advanced NSCLC
Non Small Cell Lung Cancer · ROS1 Proto Oncogene · Crizotinib
Primary: Independent Radiology Reviewed Overall Objective Response (ORR) — 88 Participants
Phase 2 N=146 A Study of Vemurafenib in Metastatic Melanoma Participants With Brain Metastases
Malignant Melanoma
Primary: Best Overall Response Rate (BORR) Within Brain of Previously Untreated Participants (Assessed by Independent Review Committee [IRC] Using Modified Response Evaluation…
Phase 2 N=127 Acupuncture for Urinary Incontinence
Urinary Incontinence
Primary: Percent Change in Incontinent Episodes — -38.26; -15.29 percent change in incontinent episodes — p=0.02
Phase 1 N=38 A Double-Blind, Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of DX-2930 in Hereditary Angioedema Participants
Hereditary Angioedema (HAE)
Primary: Number of Participants With Serious Adverse Events (SAE) and Treatment-Emergent Adverse Events (TEAE) — 0; 0; 0; 0 Participants
Phase 4 N=163 Neurogenic Intermittent Claudication Evaluation Study
Spinal Stenosis
Primary: Mean Percentage Change From Baseline in Physical Function at 1 Year Follow-up Using the Patient Completed Zurich Claudication Questionnaire — -32.31; -37.48 percentage…
Phase 2 N=97 Pediatric Head Lice Study Product Comparison
Head Lice
Primary: Number of Participants Free of Live Head Lice and Free of Viable Eggs — 57; 55; 32; 46 Participants
Phase 4 N=20 Adding Exenatide to Insulin Therapy for Patients With Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease
Nonalcoholic Fatty Liver Disease · Type 2 Diabetes Mellitus
Primary: Hepatic Steatosis — 4.0 Percentage of liver fat
N/A N=300 Supplemental Oxygen Reduces Surgical Infection
Wound Infection
Primary: Incisional Surgical Wound Infection — 22; 35 participants — p=0.04