17,261 trials
Non Alcoholic Fatty Liver Disease
Primary: Change in Serum ALT (Alanine Aminotransferase) From Baseline to Week 16 — -16.3; -6.9; -10.1 U/L — p=0.5946
Sars-CoV2 · COVID-19
Primary: Time Until Cessation of Oral Shedding of SARS-CoV-2 Virus — 13; 14 days — p=0.24
Head and Neck Cancer
Primary: Objective Response Rate (ORR) as Determined by Blinded Independent Central Review (BIRC) - Platinum Refractory Subgroup — 13.2; 18.3 percentage of participants — p=0.2897
Chronic Rhinosinusitis (Diagnosis)
Primary: Subjects Who Developed Antibiotic Resistance Organisms — 0; 0; 1; 0 Participants
Colorectal Cancer
Primary: Percentage of Participants in Objective Response (Partial or Complete Responses) — 47.5 percentage of participants
Bipolar Disorder I · Bipolar Disorder II · Major Depressive Episode
Primary: Part A: Number of Participants With at Least One Treatment-Emergent Adverse Events (TEAEs) — 16 Participants
Intraoperative Floppy Iris Syndrome
Primary: Pupil Dilation Sized of the Treated Eye Compared to the Non-treated Eye — 6.76; 7.17 millimeters
COVID-19
Primary: COVID Ordinal Outcomes Scale at 14 Days — 2.0; 2.0 score on a scale
COVID-19 Pneumonia, Impaired Respiratory Function
Primary: APACHE II Severity of Disease Score on Day 15 or on the Day of Discharge (Whichever is Earlier) — 14.5; 13.5 Score on a scale — p=0.33
COVID-19 Infection
Primary: Log10 SARS-CoV-2 Viral Load — 5.056; 5.110; -1.651; -1.881 Log 10 SARS-CoV-2 Viral Load Copies/mL
Acne Vulgaris
Primary: Safety as Measured by Reported Adverse Events — 2; 4; 5; 5 TEAEs
Malignant Glioma · Recurrent Glioblastoma
Primary: T-cell (Immunologic) Changes in Blood
Autoimmune Pulmonary Alveolar Proteinosis
Primary: Absolute Change From Baseline of Alveolar-arterial Oxygen Concentration (A-a(DO2)) After 24 Weeks of Treatment — 28.6; 29.3; 32.0 mmHg — p=0.1688
Breast Neoplasms
Primary: Part I Only: Clinical Benefit Rate (CR+PR+SD≥6months) of Patients Who Received Neratinib Alone — 5 Participants
Alcohol Use Disorder
Primary: Total Number of Standard Drinks Per Day Consumed During Natural (Usual Environment) Conditions — 6.018; 3.534; 3.998; 5.012 standard drinks per day — p=0.013