N/A N=120 A Comparison of Two Daily Disposable Soft Contact Lenses
Visual Acuity
Primary: Subjective Overall Comfort — 75.5; 70.8 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=434 A Study to Evaluate the Efficacy and Safety of Zenapax in Combination With CellCept, Cyclosporine, and Corticosteroids in Patients Undergoing Cardiac Transplantation
Heart Transplantation
Primary: Number of Participants Who Developed Acute Rejection Episode Within 6 Months Post-Transplant — 77; 104 participants — p=0.007
N/A N=36 DREAM: Does Inhaled Fluticasone REsult in Obstructive Sleep Apnea Manifestations?
Lung Disease
Primary: Number of Participants With Improved, Unchanged, and Worsened Critical Closing Pressure (Pcrit) From Baseline With 16-week of High Dose Inhaled FP Treatment. — 8; 8; 2…
Phase 3 N=219 Safety and Efficacy Study of Apremilast to Treat Psoriatic Arthritis
Psoriatic Arthritis
Primary: Percentage of Participants Who Achieved an American College of Rheumatology 20% (ACR20) Response at Week 16 — 20.2; 38.2 percentage of participants — p=0.0040
N/A N=27 Randomized Study of Failed SCS Trials Comparing Outcomes Using the Observational Mechanical Gateway (OMG) Connector
Chronic Pain
Primary: Subject's Treatment Preference — 6; 3; 1; 2 participants
Phase 2 N=457 Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid Arthritis
Rheumatoid Arthritis
Primary: American College of Rheumatology 20 (ACR20) Response at 6 Months — 53; 87; 101 Participants
N/A N=62 Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure Disorders
Accelerated Phase Chronic Myelogenous Leukemia · Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome · Adult Acute Lymphoblastic Leukemia in Remission
Primary: Day 100 TRM — 8.44 percentage of participants
Phase 3 N=173 Effect of Aspirin Pretreatment or Slow Dose Titration on Flushing and Gastrointestinal Events in Healthy Volunteers Receiving Delayed-release Dimethyl Fumarate
Healthy
Primary: Percentage of Participants Reporting Overall Flushing Events During the Overall Treatment Period, as Assessed by the Modified Flushing Severity Scale (MFSS) — 41; 91…
Phase 2 N=207 Dose-Ranging Study Of Tofacitinib In Adults With Active Ankylosing Spondylitis
Ankylosing Spondylitis
Primary: Percentage of Participants Achieving 20 Percent (%) Improvement in Assessment of SpondyloArthritis International Society (ASAS) Score (ASAS 20) at Week 12 — 56.0; 63.0…
Phase 3 N=1,021 A Study of the Addition of Avastin (Bevacizumab) to Carboplatin and Paclitaxel Therapy in Patients With Ovarian Cancer
Ovarian Cancer
Primary: Percentage of Participants With at Least One Adverse Event (AE) — 97.8 percentage of participants
Phase 3 N=265 Vitamin D Status of Pregnant Women and Their Children in Eau Claire, South Carolina
Vitamin D Deficiency · Pregnancy
Primary: 25-hydroxyvitamin D at Visit 7 — 36.7; 39.8 ng/mL
Phase 2 N=56 Anemia in Heart Failure With a Preserved Ejection Fraction (HFPEF)
Anemia
Primary: Change in Left Ventricular End-diastolic Volume — -6; -4 mL
Phase 3 N=58 A Study to Evaluate the Effects of Ezetimibe (MK-0653) on the Postprandial (Following a Meal) Lipoprotein Response in Participants With Primary Hypercholesterolemia (High Cholesterol) (MK-0653-072)(COMPLETED)
Hypercholesterolemia
Primary: Total Cholesterol Concentration of Chylomicron (Sf≥400) Fractions After a Cholesterol-Rich Test Meal — 0.45; 0.50 mg/dL — p=0.241
Phase 1 N=102 Naproxen Sodium/ASA Platelet Study
Hematology
Primary: Inhibition of Serum Thromboxane B2 (TXB2) on Day 16 at 24 Hour Post IR ASA 81 mg Administration — 93.09; 87.71; 92.87; 98.72 percentage
N/A N=276 Evaluation of the Performance of Investigational Contact Lenses in a Presbyopic Population
Presbyopia
Primary: Binocular Distance Visual Acuity (LogMAR) — -0.068; -0.058; -0.109; -0.107 LogMAR