Phase 4 N=204 Reinfusion Drains vs Tranexamic Acid in Total Joint Arthroplasty
Total Joint Arthroplasty
Primary: Blood Transfusion — 5; 8; 1 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=24 ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer
Colorectal Neoplasms · Colorectal Carcinoma · Colorectal Tumors
Primary: Maximum Tolerated Dose (MTD) of ISIS 183750 in Advanced Solid Tumors — 1000 mg
N/A N=81 Remediation of Working Memory in Schizophrenia
Schizophrenia · Schizoaffective Disorder
Primary: Cognitive Assessment - MATRICS Consensus Cognitive Battery — 40.08; 43.28; 39.80; 41.28 T-score — p=.06
Phase 2 N=128 Analyzing Female Trauma Exposed Responses to a Medication
Stress Disorders, Post-traumatic
Primary: Efficacy, Measured by Change in the Clinician-Administered PTSD Scale (CAPS) Score — -26.02; -27.33 score on a scale
N/A N=80 T-116_Procera-Bridge Zirconia - A Clinical Study
Partial Edentulism
Primary: Success Rate of Bridge Procera Bridge Zirconia — 100 percentage of successful implants — p=<0.05
Phase 4 N=40 Investigation of Maintaining Visual Performance Achieved With Cyclosporine Therapy
Dry Eye Syndromes
Primary: Change From Baseline in Total Corneal Staining Score With Fluorescein in the Worse Eye — 7.29; -1.96 Scores on a Scale
Phase 2 N=192 Safety of EVG+RTV Administered With Other Antiretroviral Agents for the Treatment of HIV-1 Infection
HIV Infections
Primary: Percentage of Participants Experiencing Any Treatment-Emergent Study Dug-Related Adverse Event — 14.6 percentage of participants
Phase 4 N=2,252 A Study of Avastin (Bevacizumab) in Combination With Platinum-Containing Chemotherapy in Patients With Advanced or Recurrent Non-Squamous Cell Lung Cancer.
Non-Squamous Non-Small Cell Lung Cancer
Primary: Number of Participants With Adverse Events of Special Interest — 687; 672; 26; 30 participants
Phase 2 N=97 Prevention and Acute Treatment of Chronic Cluster Headache Compared to Standard of Care
Chronic Cluster Headache
Primary: A Change in the Frequency of Cluster Headache Attacks Per Week — -2.0; -7.6 CH attacks per week
N/A N=837 Telephone Case Monitoring (TCM) for Veterans With Post-Traumatic Stress Disorder (PTSD)
Stress Disorders, Post-Traumatic
Primary: Aggressive Behavior; Alcohol Misuse; Drug Misuse; PTSD Symptoms — 63.9; 63.4; 3.0; 3.1 Scores on a scale
N/A N=51 Evaluation of the Rapid Airway Management Positioner
Endotracheal Intubation · Rapid Airway Management Positioner
Primary: Ease of Mask Ventilation as Assessed by Han Class — 15; 24; 18; 15 participants — p=0.0003
N/A N=30 A Comparison of Postoperative Analgesic Nerve Block Ropivacaine Concentrations
Total Hip Arthroplasty · Postoperative Pain
Primary: Opiate Consumption Postoperatively — 8.21; 8.02 mg
Phase 1 N=48 A Study of Obinutuzumab in Chinese Participants With CD20+ Malignant Disease
Lymphocytic Leukemia, Chronic, Diffuse Large B-cell Lymphoma, Follicular Lymphoma
Primary: Area Under the Serum Concentration Time Curve From Zero to Day 7 (AUC0-7) of Obinutuzumab on Day 1, Cycle 1 — 1458; 1750; 1647 day*micrograms per milliliter
N/A N=74 Educational Program for Hearing Aid Users With Internet Support
Hearing Impaired
Primary: The Hearing Handicap Inventory for the Elderly (HHIE) — 42.0; 36.1; 35.8; 31.3 units on a scale — p=0.685
Phase 2 N=62 D1 and D2 Dopamine Receptors in Gambling and Amphetamine Reinforcement
Pathological Gambling
Primary: Subjective Reinforcement Self-report Scales — 4.8; 4.8; 9.5; 9.3 units on a scale