17,261 trials
Hypertriglyceridemia
Primary: Percent Change in Plasma Triglycerides (Pharmacodynamic Population) — -20.9; -18.3 Percent Change from baseline
Lung Transplant Infection
Primary: Number of Participants Free From New or Progressive Chronic Lung Allograft Dysfunction — 2; 4 Participants
Heart Failure, Diastolic
Primary: Change in Health Status of Patients With HFpEF — 4.15; 26.56; 29.97; 33 Scores on a scale
Palmoplantar Pustulosis
Primary: Log Transformed Ratio of Postbaseline Fresh Pustule Count at Day 28 to Baseline — 0.86; 0.53 Log transformed ratio — p=0.24
Marginal Zone Lymphoma · MZL
Primary: Overall Response Rate (ORR) by Independent Review Committee (IRC) Assessment — 68.2 Percentage of participants — p=<0.0001
COVID-19
Primary: Time-weighted Average Change From Baseline in Nasopharyngeal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Viral Load Through Day 7 — -2.04; -1.51; -1.24…
Major Depression
Primary: Model Adjusted Means for Hamilton Depression Rating Score — 20.22; 20.56 score on a scale — p=0.68
COVID-19 Pulmonary Complications · COVID-19
Primary: Number of Participants With Respiratory Failure-free Survival — 27; 28 Participants — p=0.4099
Ann Arbor Stage I Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue · Ann Arbor Stage II Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue · Extranodal Marginal Zone Lymphoma
Primary: Relapse-free Survival (RFS) — 83 months
Recurrent Plasma Cell Myeloma · Refractory Plasma Cell Myeloma
Primary: ORR Evidenced by Confirmed Response Rate, Defined as Number of Patients With Partial Response or Better by International Myeloma Working Group (IMWG) Criteria Divided by…
Osteogenesis Imperfecta, Type I · Osteogenesis Imperfecta Type III · Osteogenesis Imperfecta Type IV
Primary: Change From Baseline in Radial Trabecular Volumetric Bone Mineral Density (Tr vBMD) at Month 12 — 1.004; 0.993; 0.992 ratio — p=0.644
Metastatic Carcinoma in the Liver · Recurrent Colorectal Carcinoma · Stage IV Colorectal Cancer AJCC v7
Primary: Change in Tumor-infiltrating Lymphocytes (TILs) in the Colorectal Cancer Lesions — 7.25 fold change — p=0.046
Sturge-Weber Syndrome
Primary: Number of Seizures Per Month — 33.5; 30.0; 3.0; 0.5 Seizures per month
Cervical Cancer · Uterine Cancer · Vaginal Cancer
Primary: Mean Doses Given — 93.9; 63.2; 58.63 Gy
Coronavirus Disease 2019
Primary: Number of Participants With at Least 1 Serious Adverse Event — 3; 6 Participants