Phase 2 N=25 Phase II Study of Gamma Knife Radiosurgery and Temozolomide for Brain Metastases
Cancer · Brain Metastases
Primary: Percentage of Participants With Distant Brain Failure (DBF) at One Year — 37 percentage of participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=49 Febuxostat, Blood Pressure and the Intrarenal Renin-Angiotensin System (RAS)
Hypertension
Primary: Change in Renal Plasma Flow in Response to Infused Angiotensin II — -54.1; -10.8 ml/minute
N/A N=187 Hypnosis For Hot Flashes Among Postmenopausal Women in a Randomized Clinical Trial
Hot Flashes
Primary: Hot Flash Frequency — 27.19; 68.26; 19.44; 62.32 hot flashes per week
Phase 1 N=96 Safety, Antiviral Activity and PK of MRD of BI 201335 in Chronic Hepatitis C Patients Both Treatment Naive and -Experienced
Hepatitis C, Chronic
Primary: Efficacy: VR (Virologic Response) of >=2 log10 Reduction in Plasma Hepatitis C Virus (HCV) Ribonucleic Acid (RNA) From Baseline at Any Time up to Day 14 (naïve Patients)…
N/A N=41 Vocal Warm-up and Respiratory Muscle Training
Voice Disorders
Primary: Voice Handicap Index (VHI-10) — 20.44; 13.82 units on a scale — p=0.001
Phase 2 N=45 Combined Modality Therapy for Patients With With HIV and Stage I, Stage II, or Stage III Anal Cancer
Anal Cancer
Primary: Locoregional Failure Rate at 3 Years — 42; 20 percentage of participants
Phase 2 N=43 Treatment of Cocaine Dependence With Lisdexamfetamine
Cocaine Dependence
Primary: Cocaine-positive Urine Results — 86.5; 92.4 percentage of BE urine tests
N/A N=106 Oxytocin's Effect on Socioemotional Aging
Aging
Primary: Extent of Trust Behavior — 39.03; 44.42; 45.11; 46.06 monetary units
N/A N=6,617 Observational Data Analysis in EuroSIDA (MK-0518-058)
HIV-1 Infections
Primary: Incidence of Malignancy — 1.29; 1.17; 0.81 Events per 100 person-years of follow-up
Phase 4 N=100 Desflurane or Propofol Anesthesia in Elderly Obese Patients Undergoing Total Knee Replacement
Obesity · Arthritis
Primary: Assessment of Delirium — 0; 0 participants
N/A N=75 VISIBILITY™ Iliac Study
Peripheral Arterial Disease · Claudication
Primary: Major Adverse Event Rate at 9 Months — 4.0 percentage of participants
Phase 1 N=20 Study to Assess the Effect of BMS-790052 on the Pharmacokinetics of Ortho Tri-Cyclen® in Healthy Female Subjects
Chronic Hepatitis C
Primary: Maximum Observed Plasma Concentration (Cmax) of Ethinyl Estradiol — 118.53; 134.70 picogram per millilitre (pg/mL)
N/A N=34 EverFlex™ Self-expanding Peripheral Stent With Entrust™ Delivery System Clinical Study
Peripheral Arterial Diseases
Primary: Absence of Stent Elongation — 95.6 percentage absence of stent elongation
N/A N=30 Model Driven Diabetes Care
Diabetes Mellitus, Type 1
Primary: Change in the Frequency of Hyper- and Hypo-glycemic Events From Baseline to Week 8-12. — -18; -7.5 Events
Phase 2 N=436 Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee
Knee Osteoarthritis
Primary: Change in WOMAC A — -91.8; -110.0; -109.8; -93.7 units on a scale — p=<0.05