N/A
Completed N=106
Oxytocin's Effect on Socioemotional Aging
Source: ClinicalTrials.gov NCT01823146 ↗Enrolled (actual)
106
Serious AEs
0.0%
Results posted
Sep 2015
Primary outcomePrimary: Extent of Trust Behavior — 39.03; 44.42; 45.11; 46.06 monetary units
Summary
This study will investigate the extent to which intranasal oxytocin affects changes in social decision making and evaluations of others. Oxytocin is a hormone that naturally occurs in the body and the brain and has been shown to be relevant for many behaviors, particularly in social situations. Research on the effects of oxytocin in aging is very scarce; therefore, the purpose of this research project is to determine the effects of oxytocin on socioemotional aging.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Extent of Trust Behavior |
39.03; 44.42; 45.11; 46.06 | — |
| SECONDARY Meta-Mood |
3.38; 2.977; 3.23; 3.63; 3.54; 3.58 | — |
| SECONDARY Functional Connectivity (Resting fMRI) |
0.58; 0.48 | — |
Eligibility Criteria
Inclusion Criteria
- Between the ages of 18-30 years or 63-85 years
- English fluency
- Caucasian
- Right-handed
Exclusion Criteria
- Pregnant or possibly pregnant
- Breastfeeding
- Claustrophobia
- Currently on vasoconstrictors, pseudoephedrine or antidiuretic medication
- Large pieces of metal in the body, particularly in the face or neck
- Piercings or metal implants that cannot be removed from the body
- Surgery on the brain or any prior serious brain damage or disease
- Dementia or severe cognitive disorders
- History of hyponatremia, Syndrome of Inappropriate Antidiuretic Hormone, psychogenic polydipsia, or motion disorder
Data sourced from ClinicalTrials.gov (NCT01823146). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.