65,437 trials
Schizophrenia
Primary: Unbound Brexpiprazole Area Under the Concentration Time Curve (AUC) Calculated to the Last Observable Concentration at Time t (AUCt,u) — 5.95; 4.87; 5.41; 4.28…
Anaplastic Large Cell Lymphoma · Angioimmunoblastic T-cell Lymphoma · Hepatosplenic T-cell Lymphoma
Primary: Overall Response (OR) Rate — 0.07 Proportion of participants
Cure Rate
Primary: 28-day Cure Rate — 63.67 Percentage of participants
Breast Cancer
Primary: Progression-free Survival (PFS) Assessed by the Independent Review Panel According to Response Evaluation Criteria for Solid Tumors (RECIST) 1.1 — 166; 165 days…
Patients With Moderate to Severe Perioral Lines
Primary: Percentage of Participants With at Least a 1 Point Improvement From Baseline on the Perioral Lines Severity Scale (POLSS) — 87; 72 percentage of participants
Stress Disorders, Post-Traumatic
Primary: Clinician-Administered PTSD Scale (CAPS) Diagnostic and Statistical Manual, 4th ed., Text Revision (DSM-IV) — 77.46; 75.61; 52.39; 62.07 units on a scale — p=<.006
Cystic Fibrosis, Homozygous for the F508del CFTR Mutation
Primary: Absolute Change From Baseline in Percent Predicted Forced Expiratory Volume in 1 Second (FEV1) at Week 24 — -0.15; 2.46; 2.85 percent predicted of FEV1 — p=0.0004
Oliguria · Polyuria
Primary: Urine Output of SOC Device Versus Accuryn — 0; 5 Patients with airlocks
Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma · Recurrent Metastatic Squamous Neck Cancer With Occult Primary · Recurrent Salivary Gland Cancer
Primary: Progression Free Survival (PFS) — 3; 3.2 months
Obstructive Sleep Apnea · Stroke · Transient Ischemic Attack
Primary: Sleep Apnea Diagnosis Rate — 58; 5 participants
Glabellar Rhytides
Primary: Percentage of Subjects With a ≥ 1-Grade Improvement From Day 1 in the Investigator Assessed Facial Wrinkle Scale of Glabellar Rhytides at Maximum Contraction — 97.1…
Anaesthesia
Primary: Postoperative Pharyngolaryngeal Morbidity Postoperative 1.Hour — 1; 1 units on a scale
Knee Osteoarthritis
Primary: Clinical Flexion — 119.1; 120.3; 112.0; 111.3 degrees
Schizophrenia
Primary: Change From Baseline in PANSS Total Score at Day 42 — -17.4; -21.7; -21.6; -16.2 score on a scale — p=0.6043
Healthy
Primary: Empa: Area Under the Curve 0 to Infinity (AUC0-∞) — 2560; 2530; 986; 968 nmol*h/L