Phase 3 Completed N=225 Randomized Treatment

Diagnosis and Treatment of Sleep Apnea in Cerebrovascular Disease

Obstructive Sleep Apnea · Stroke · Transient Ischemic Attack · Hypertension

Source: ClinicalTrials.gov NCT00984308 ↗

Enrolled (actual)

225

Serious AEs

3.1%

Results posted

Sep 2015

Primary outcomePrimary: Sleep Apnea Diagnosis Rate — 58; 5 participants

Summary

Sleep apnea is common among Veterans with cerebrovascular disease (stroke or transient ischemic attack [TIA]), leads to hypertension, and is associated with recurrent stroke and death. Although continuous positive airway pressure (CPAP) safely treats sleep apnea, few Veterans with cerebrovascular disease are diagnosed with sleep apnea or offered treatment.

Outcome Measures

Outcome	Result	p-value
PRIMARY Sleep Apnea Diagnosis Rate	58; 5	—
PRIMARY Hypertension Control	157.4; 161.6	—
SECONDARY Sleep Apnea Treatment Rate	22; 0	—

Eligibility Criteria

Inclusion Criteria

Stroke or Transient Ischemic Attack Hypertension

Exclusion Criteria

Prior diagnosis of sleep apnea or other sleep disorder
Life expectancy < 6 months or Hospice
Non-English speaker
Unable/unwilling to use mask
Inability to give informed consent
Oxygen dependent COPD
Chronic renal failure with dialysis
Active Suicidal Ideation

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00984308). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.