65,437 trials
Psoriasis
Primary: Percentage of Patients Who Are Clear (PGA Score 0) or Have Minimal Disease (PGA Score 1) on Each Treated Side at Each Visit. — 33.3; 6.7; 46.2; 15.4 percentage of…
Recurrent Plasma Cell Myeloma · Refractory Plasma Cell Myeloma
Primary: Overall Response Rate — 2; 0; 0; 1 participants
Malaria
Primary: Time to Parasite Clearance — 23.63; 44.97; 48.75 Hours
Advanced Solid Malignancies · Malignant Lymphoma
Primary: Best Objective Response Based on RECIST Criteria (Evaluable for Response Analysis Set for RECIST Criteria) — 0; 0; 0; 0 Participants
Cystic Fibrosis
Primary: Change in FEV1 From Baseline to End of Treatment at Day 168 — 0.08; 0.06 liters
Lumbar Spinal Stenosis
Primary: Percentage of Participants With a 2-point Improvement in Visual Analogue Scale — 65.71; 46.15 percentage of responders
Mevalonate Kinase Deficiency
Primary: Number of Flares Per Participant During Historical Period and Treatment Period — 5; 0 Number of flares
Healthy
Primary: Difference in RAVLT Total T-Score Between Treatments — 57.76; 56.11; 53.08; 42.76 T-score — p=<0.01
Asthma
Primary: Participants With Adverse Experiences During Weeks 0-12 (Double-Blind Period) — 105; 84; 6; 3 participants
Hypertension
Primary: Change From Baseline in Mean Sitting Diastolic Blood Pressure (msDBP) — -11.53; -10.98; -12.45; -3.69 mmHg
Cancer Related Fatigue
Primary: Retention Rate in Study (Feasibility Outcome) — 0.80; 0.65 proportion of participants
Recurrent Colon Cancer · Recurrent Rectal Cancer · Stage IV Colon Cancer
Primary: Objective Tumor Response (Defined as Partial or Complete Response as Defined by the RECIST Criteria) — 1 participants
Hepatitis · Hepatitis C
Primary: Number of Randomized Patients Achieving Early Virologic Response (EVR) - Negative PCR Result for HCV RNA (< 15 IU/ml) or ≥ 2log10 Decrease of Viral Load After 12 Weeks…
Essential Hypertension
Primary: Change in Mean 24-hour Ambulatory Blood Pressure Monitoring (ABPM) Systolic Blood Pressure (maSBP) — -13.93; -0.82 mmHg
Cryopyrin-associated Periodic Syndromes · Familial Cold Autoinflammatory Syndrome · Muckle-Wells Syndrome
Primary: Percentage of Participants Aged 4 Years or Younger With at Least One Complete Response at Week 56 — 94.1 Percentage of participants