Phase 4 N=162 Evaluate Analgesic/Sedative Efficacy of Naproxen Sodium and Diphenhydramine
Sleep
Primary: Total Sleep Time Measured by Actigraphy — 339.80; 304.60; 413.89; 308.89 Minutes — p=0.54
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=742 Comparative Efficacy of Dutasteride Plus Tamulosin With Lifestyle Advice Versus Watchful Waiting Plus Lifestyle Advice in the Management of Treatment naïve Men With Moderately Symptomatic Benign Prostatic Hyperplasia and Prostate Enlargement
Prostatic Hyperplasia
Primary: Change From Baseline in the Total International Prostate Symptom Score (IPSS) at Months 1, 3, 6, 9, 12, 15, 18, 21, and 24 Using the Last Observation Carried Forward…
Phase 4 N=23 Open Label Use Of RiaStap During Aortic Reconstruction
Coagulopathic Bleeding
Primary: Fibrinogen Level Change — 317; 235; 331; 312 mg/dl
Phase 4 N=27 Does Pharmacological Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in Adults Enhance Parenting Performance?
ADHD
Primary: Dyadic Parent-Child Interaction Coding System (DPICS) - Behavior Counts — 67.2; 42.1; 53.8; 40.1 behaviors
Phase 4 N=16,492 Does Saxagliptin Reduce the Risk of Cardiovascular Events When Used Alone or Added to Other Diabetes Medications
Type 2 Diabetes Mellitus
Primary: Participants With Any Event From the Composite of Cardiovascular Death (CV Death), Non-fatal Myocardial Infarction (MI), or Non-fatal Ischaemic Stroke — 613; 609…
Phase 4 N=258 CAMEO: Canadian Methotrexate and Etanercept Outcome Study
Rheumatoid Arthritis
Primary: Change From Month 6 to Month 12 in Disease Activity Sscore 28 (DAS28) — -0.39; 0.02 scores on a scale
Phase 4 N=191 Efficacy of Changing to TRAVATAN® From Prior Therapy
Open-angle Glaucoma · Ocular Hypertension
Primary: Change in Intraocular Pressure (IOP) at 12 Weeks From Prior Therapy (Baseline) — 14.8; -1.09 mmHg
Phase 4 N=90 Dipeptidyl Peptidase-4 Inhibitor (Sitagliptin) Therapy in the Inpatients With Type 2 Diabetes
Type 2 Diabetes Mellitus · Hospitalization · Hyperglycemia
Primary: Mean Blood Glucose Levels Among the Three Groups at the Time of Hospitalization to 1st Day After Therapy — 209; 203; 225; 168.4 mg/dl
Phase 4 N=129 Topical Antibiotics and Intravitreous Injections
Intravitreous · Injections
Primary: Positive Culture — 8 percentage of patients
Phase 4 N=70 Effectiveness of Armodafinil for Treating Fatigue in Adults With HIV/AIDS
HIV Infections · Fatigue
Primary: Fatigue Severity Scale(FSS) Outcome — 52.6; 53.1; 25.8; 39.4 units on a scale — p=<0.001
Phase 4 N=396 TReatment of Atrial Fibrillation With Dual dEfibrillator in Heart Failure Patients
Heart Failure, Congestive
Primary: Unplanned Hospital Admissions for Cardiac Reasons OR Death of Cardiovascular Causes OR Progression to Chronic Atrial Fibrillation — 43; 44 participants
Phase 4 N=1,166 MINERVA: MINimizE Right Ventricular Pacing to Prevent Atrial Fibrillation and Heart Failure
Atrial Fibrillation · Heart Failure, Congestive
Primary: Composite Endpoint Composed by Death for Any Cause, Cardiovascular Hospitalization or Permanent AF at 2 Years — 28.0; 23.1; 21.5 percentage of participants
Phase 4 N=100 The Use of Dual Chamber ICD With Special Programmed Features to Lower the Risk of Inappropriate Shock
Ventricular Tachycardia · Ventricular Fibrillation · Atrial Fibrillation
Primary: Number of Subjects Inappropriately Shocked by Implantable Cardioverter-Defibrillator (ICD) — 1; 1 Participants — p=1.0
Phase 4 N=436 Efficacy and Safety of Fluvastatin Sodium Extended Release Tablets 80 mg Once Daily in Chinese Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia
Lipid Metabolism Disorders
Primary: Mean Percent Change in LDL-C From Baseline at Study Endpoint, Week 12 (LOCF) — -8.692; -7.887 Percent change
Phase 4 N=130 Insulin Detemir Versus NPH Insulin In Hospitalized Patients With Diabetes
Type 2 Diabetes
Primary: Mean AM BG (mg/dl) — 144; 155 mg/dl