65,437 trials
Kidney Transplantation
Primary: Calculated Glomerular Filtration Rate (GFR) Using the Modification of Diet in Renal Disease (MDRD) Equation — 67.06; 65.99; 67.05; 64.97 mL/min/1.73 m^2
Surgical Procedure, Unspecified
Primary: Change in Intracuff Pressure — -11.8; -9.5 cmH2O
Dental Caries
Primary: Change in Urinary Bisphenol A Level (BPA) From Baseline to 6 Months — 0.29 ng/mL — p=0.58
Dry Eye Syndrome
Primary: Mean Change From Baseline in Total Ocular Surface Staining (TOSS) Score at Day 35 (Phase I) — -2.2; -1.7 units on a scale
Respiratory Syncytial Virus Infection
Primary: Number of Subjects With Adverse Events (AEs), Serious AEs (SAEs), and Adverse Drug Reactions (ADRs) — 126; 3; 46; 3 participants
Insulin Resistance
Primary: Insulin Sensitivity by Hyperinsulinemic-euglycemic Clamp at Baseline and 6 Month Follow up — 10.92; 10.39; 10.16; 10.80 mg/kg FFM/min
Magnetic Resonance Imaging (MRI); Cardiac Pacing
Primary: MRI and Pacing System Related Serious Adverse Device Effect (SADE) Free Rate — 99.5 percentage of participants
Hepatitis B, Chronic
Primary: Percentage of Participants With Sustained Viral Response (SVR) Defined as HBV DNA ≤ 2000 IU/ml at IL28B Genotype rs12979860 at End of Follow-up (EoF) — 20.0; 17.1; 20.0…
Leukemia · Myelodysplastic Syndromes
Primary: Complete and Partial Remission Per the International Working Group (IWG) Criteria for Myelodysplastic Syndromes (MDS) or Acute Myeloid Leukemia (AML) — 30; 25; 10…
Pulmonary Disease, Chronic Obstructive
Primary: Mean Change From Baseline (BL) in Aortic Pulse Wave Velocity (aPWV) at the End of the 24-week Treatment Period (Day 168) — -1.97; -1.95; -1.75 meters per second (m/sec)…
Alzheimer's Disease
Primary: Change in Reader Accuracy After Application of Quantitation Software — 0.0746 Net Reclassification Index — p=0.0001
Systemic Mastocytosis, Aggressive (ASM) · Leukemia, Mast Cell · Hematological Non-mast Cell Lineage Disease (AHNMD)
Primary: Subjects With Clinical Response [Partial Response (PR) + Complete Response (CR)] — 25 participants
Orthostatic Intolerance · Postural Tachycardia Syndrome
Primary: Maximal Oxygen Consumption Capacity (VO2 Max) — 27.6; 24.5 mL/kg/min
Acute Pain
Primary: Cmax — 3290.70; 2785.90 ng/mL
Cancer Cachexia
Primary: ACTIVATION/NON ACTIVATION OF SPECIFIC BRAIN AREAS, EVALUATED BY FUNCTIONAL MAGNETIC RESONANCE — 585.57; 667.92; 511.22 BOLD