N/A N=50 Performance Evaluation of the Depth of Anesthesia Monitors in Pediatric Surgery
Anesthesia · Child
Primary: BISPECTRAL Index — 0.6; 0.66; 0.73 units on a scale — p=<0.01
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=5,117 Periodontal Disease Prevention Study
Periodontitis
Primary: Percentage of Participants With Tooth Loss Over 16 Year Period — 16.4; 13.8; 22.1; 16.9 percentage of participants
N/A N=18 Treatment of Suicidal Ideation With Intravenous Ketamine Infusion
Depression · Suicidal Ideation
Primary: Suicidality — 7.3; 21.5; 18.0; 0 units on a scale
Phase 1 N=52 Safety and Pharmacokinetics of MMX Mesalamine in Children and Adolescents With Ulcerative Colitis
Ulcerative Colitis
Primary: Area Under the Plasma Concentration Versus Time Curve (AUC) of MMX Mesalamine (5-ASA) at Steady State — 21411; 46173; 49213 ug*h/L
N/A N=174 Tooth Sensitivity Relief by Two Mouthrinses
Dentin Sensitivity
Primary: Mean Tactile Sensitivity Score at Week 6 — 37.91; 36.77; 30.16 grams — p=0.811
N/A N=118 Weight Management for Improved Pregnancy Outcomes
Obesity · Pregnancy
Primary: Maternal Weight Change — 1.2; -2.6 kg
N/A N=36 Staging of Axillary Lymph Nodes Using the PEM Flex Solo II Pet Scanner in Patients With Breast Cancer
Breast Cancer
Primary: Sensitivity and Specificity of FDG Positron Emission Mammography (PEM) in Identifying Axillary Lymph Node (ALN) Metastases From Breast Cancer — 83.3; 52.0 percentage of…
Phase 2 N=3,901 A Stage-Based Expert System for Teen Dating Violence Prevention
Violence · Bullying
Primary: Number of Participants Perpetrating Physical Dating Violence During Follow-up — 240; 307 participants — p=<.0001
Phase 4 N=79 Investigate the Impact of Early Treatment Initiation With Tiotropium in Patients Recovering From Hospitalization for an Acute COPD Exacerbation 1
Pulmonary Disease, Chronic Obstructive
Primary: Change From Baseline of Trough FEV1 at 12 Weeks on Study Drug — -0.051; 0.183 Litres
N/A N=112 Immediate Postplacental Insertion of IUDs at Time of Cesarean Delivery: A Randomized Clinical Trial
Intrauterine Devices · Cesarean Section
Primary: IUD Use — 32; 40 participants
Phase 4 N=161 Investigating Efficacy and Safety of Biphasic Insulin Aspart 50 Twice Daily Versus Biphasic Human Insulin 50 Twice Daily Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes Mellitus
Diabetes · Diabetes Mellitus, Type 2
Primary: 2-hour PPG (Postprandial Plasma Glucose) Increment Following a Standard Meal Test — 5.30; 6.41 mmol/L — p=< 0.001
Phase 2 N=18 A Pilot Study to Evaluate the Use of C1 Esterase Inhibitor (Human) in Patients With Acute Antibody-Mediated Rejection
Graft Rejection
Primary: Change From Baseline in Histopathology Endpoints — -45.0; -36.1; -6.0; 12.6 scores on a scale — p=0.6498
N/A N=104 Study of a Healthy Lifestyle Intervention for Deaf Adults Who Are Overweight or Obese
Overweight · Obesity
Primary: Weight Change — -5.33; -1.98 kilograms
N/A N=300 Observational Program to Assess Use of Intermittent Adjuvant Deprivation Therapy With Leuprorelin (Lucrin Depot) in Patients With Advanced Prostate Cancer (PCa) in Russia
Prostate Cancer
Primary: Mean Duration of Leuprorelin Exposure — 19.74; 21.25; 13.62 Months
Phase 1 N=26 Safety Study of Lisinopril in Children and Adolescents With a Kidney Transplant
Hypertension
Primary: Pharmacokinetics (PK) - Area Under the Plasma Concentration-time Curve (AUC) — 298; 640; 702 ng*h/mL