Phase 4 N=249 Daptomycin Versus Vancomycin in Participants With Skin Infections Due to MRSA
Staphylococcal Skin Infections
Primary: Infection-Related Hospital Length of Stay — 91.46; 93.23 Hours
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=2,583 Irritable Bowel Syndrome With Diarrhea (IBS-D) Rifaximin Re-Treatment Study
Irritable Bowel Syndrome With Diarrhea
Primary: Repeat Treatment Responders — 32.6; 25.0 percentage of patients — p=0.0232
Phase 3 N=792 Study Comparing Carfilzomib, Lenalidomide, and Dexamethasone (CRd) vs Lenalidomide and Dexamethasone (Rd) in Subjects With Relapsed Multiple Myeloma
Relapsed Multiple Myeloma
Primary: Progression-free Survival (PFS) — 17.6; 26.3 months — p=< 0.0001
N/A N=181 Zoledronic Acid for Osteoporosis in the Elderly
Osteoporosis · Bone Loss · Fragility Fractures
Primary: Bone Mineral Density (BMD) of the Total Hip and Spine — 4.5; 0.7; 3.0; 1.1 Percent change
Phase 4 N=525 An Effectiveness Trial of Maintenance Therapy for Nicotine Dependence
Nicotine Dependence
Primary: Point Prevalence Abstinence — 84; 35 participants
Phase 2 N=64 Roflumilast Plus Montelukast in Adults With Severe Asthma
Asthma
Primary: Change From Baseline in Pre-Dose (Trough) Pre-Bronchodilator Forced Expiratory Volume in 1 Second (FEV1) — 0.18; 0.08 liters — p=0.013
N/A N=101 An Observational Study of Fecal Calprotectin as Clinical Tool in Monitoring Moderate-to-severe Crohn's Disease on Adalimumab Induction Therapy: a KoRean Experience (FAIR)
Crohn's Disease
Primary: Percentage of Participants With Fecal Calprotectin Less Than 150 Microgram/Gram — 16.30; 13.25 Percentage of participants
N/A N=70 Atomoxetine for Attention Deficit Hyperactivity Disorder in Adolescents With Substance Use Disorder
Attention Deficit Hyperactivity Disorder · Substance Abuse
Primary: Change in Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) Attention-deficit/Hyperactivity Disorder (ADHD) Checklist — 18.61; 18.19 units on a…
N/A N=146 Post Operative Walking Enhancements for Recovery (POWER) Trial
External Causes of Morbidity and Mortality
Primary: Number of Steps Taken in 24 Hours. — 80; 87 Steps — p=.70
N/A N=555 Multi-country Post-Marketing Observational Study on Maintenance of Effectiveness of Adalimumab (Humira®) in Patients With Ankylosing Spondylitis and Psoriatic Arthritis
Ankylosing Spondylitis · Psoriatic Arthritis
Primary: Percentage of Participants With a 50% or More Decrease in Bath Ankylosing Spondylitis Daily Activity Index (BASDAI) Score at 12 Months Relative to Baseline — 76.5; 73.1…
N/A N=120 Healthy Eating for Colon Cancer Prevention
Colon Cancer
Primary: Adherence to Dietary Goals — 89; 85 percentage of participants meeting goals
Phase 3 N=150 Efficacy of Oral Famciclovir 125mg Comparing to Aciclovir 200 mg Treatment in Patients With Active Recurrent Genital Herpes
GENITAL HERPES
Primary: Efficacy Will be Evaluated by the Proportion of Subjects With Non Herpes Manifestation — 73; 52 subjects
Phase 2 N=46 Study of Bevacizumab/Doxil in Treatment of Platinum-Resistant/Refractory Ovarian Cancer (CA)
Ovarian Cancer
Primary: Progression Free Survival (PFS) by RECIST Criteria — 7.8 Months
Phase 3 N=152 Preoperative Single-dose Steroid Application for the Treatment of Nausea and Vomiting After Thyroid Surgery
Thyroidectomy · Thyroid Diseases
Primary: Incidence of Postoperative Nausea and Vomiting — 29; 57 percentage of participants — p=0.001
Phase 3 N=192 Rollover Study of VX-770 in Cystic Fibrosis Subjects
Cystic Fibrosis
Primary: Number of Participants With Non-Serious Adverse Events (AEs) and Serious Adverse Events (SAEs) — 190; 70 participants