N/A N=62 The Effect of Experimental Dentifrices on Remineralization of Caries Lesions In-situ
Oral Hygiene
Primary: Percentage Surface Microhardness Recovery (% SMHR) — 32.49; 31.81; 27.56; 22.62 Percentage of SMHR — p=<0.0001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=39 Treatment of Preclinical Hypertrophic Cardiomyopathy With Diltiazem
Hypertrophic Cardiomyopathy
Primary: Increase, Stability of, or Decrease in the Decline of Diastolic Function as Reflected by the Global Early Myocardial Relaxation (E') Velocity — -0.06; -0.21 cm/sec…
Phase 3 N=50 Safety and Tolerability Study of GlaxoSmithKline (GSK)1557484A Vaccine in Adults at Occupational Risk for Influenza A (H5N1) Exposure
Influenza · Influenza Vaccines
Primary: Number of Subjects Reporting Any and Grade 3 Solicited Local Symptoms Overall and by Age Category (18-64 and >64 Years of Age). — 45; 1; 46; 4 Participants
Phase 3 N=110 Randomized Switch Study From Hydroxyurea to Ruxolitinib for RELIEF of Polycythemia Vera Symptoms: The Relief Study
Polycythemia Vera
Primary: Percentage of Subjects Achieving a ≥ 50% Improvement From Baseline in Total Symptom Score-Cytokine (TSS-C) at Week 16, as Measured by the Modified Myeloproliferative…
Phase 3 N=415 Study of AA4500 in the Treatment of Peyronie's Disease
Peyronie's Disease
Primary: Percentage Change From Baseline in Penile Curvature — -30.5; -15.2 percentage of curvature change — p=.0059
N/A N=219 Non-Pharmacological Interventions on Sleep in Post-Acute Rehabilitation
Sleep Disorders
Primary: Pittsburgh Sleep Quality Index — 8.6; 9.4 units on a scale; 0-21 — p=0.10
N/A N=300 The Effect of Age on the Incidence of Postoperative Residual Neuromuscular Blockade
Residual Neuromuscular Blockade in Elderly Patients
Primary: Incidence of Residual Neuromuscular Blockade — 45; 86 participants
N/A N=18 PK Analysis of Moxifloxacin in the Treatment of CAP
Pneumonia
Primary: Total Peak Plasma Concentration (Cmax) — 3.99 mg/L
Phase 3 N=38 A Study to Test the Use of Duloxetine for Pain in MS
Multiple Sclerosis
Primary: Percent Change in Worst Pain Score — -29.1; -11.5 percent reduction on 0-10 analog scale — p=0.016
N/A N=11 Acute Cardiovascular and Metabolic Effects of Exercise Training in Individuals With Insulin Resistance
Insulin Resistance
Primary: Insulin Sensitivity After 5-7 Days of Exercise — 3; 2.5 index score — p=<0.05
Phase 3 N=1,432 Study on Prolonging Bone Metastasis-Free Survival in Men With Hormone Refractory Prostate Cancer
Hormone Refractory Prostate Cancer
Primary: Bone Metastasis-free Survival — 768.0; 897.00 days — p=0.0284
Phase 3 N=355 Prevention of Invasive Fungal Infections (IFIs) in Subjects Receiving Chemotherapy for Acute Lymphoblastic Leukemia
Invasive Fungal Disease
Primary: Percentage of Participants With Proven or Probable IFIs During Remission-induction Chemotherapy for Acute Lymphoblastic Leukemia (ALL) — 7.9; 11.7 percentage of…
N/A N=22 Initial Effects of Kinesiotaping in Non Surgical Treatment of Hallux Valgus
Hallux Valgus · Pain
Primary: Adduction Angle of Hallux With X RAY — 22.6; 19.3 degrees
Phase 1 N=5 Viral Kinetics in HCV Clearance in Subjects With Hemophilia
Chronic Hepatitis C · Hemophilia
Primary: Number of Participants With Sustained Virological Response at Week 12 (SVR12) — 2; 2 participants
N/A N=10 Beetroot Juice as a Potential Ergogenic Aid During Exercise in Hypoxia
Hypoxia
Primary: Time to Complete a 10 km Run — 2862; 2874 Seconds