65,437 trials
Influenza
Primary: Hemagglutination Inhibition (HI) Geometric Mean Titers (GMT) Post-vaccination (Day 28) of Each Vaccine Reference Virus — 584.2; 342.8; 217.4; 169.0 antibody titer…
Post Traumatic Stress Disorder
Primary: Posttraumatic Stress Disorder Checklist (PCL-5) — 44.30; 43.38; 22.51; 25.11 score on a scale
Depression · Major Depressive Disorder · tACS
Primary: Change in Hamilton Depression Rating Scale 17-item (HDRS-17) — -12.04 units on a scale — p=<0.0005
Prostatic Neoplasms · Genital Neoplasms, Male · Urogenital Neoplasms
Primary: Primary Endpoint (HIFU): Identification of New Cancers — 85; 49 biopsy-proven cancerous zones
Chemotherapy-Induced Alopecia
Primary: Dose-limiting Toxicities (DLT) of Topical Compound 31543 — 0; 0; 0; 0 Participants
Sickle Cell Crisis
Primary: Pain Scores — 5.6; 5.7 score on a scale
Skin Squamous Cell Carcinoma · Appendix Adenocarcinoma · Rare Lesion
Primary: Overall Response Rate (ORR) — 2 Participants
Hematologic Malignancies
Primary: Disease-free Survival (DFS) — 57; 29; 38; 57 percentage of participants
Smoking, Tobacco · Mental Illness
Primary: Study 3: Smoking Abstinence — 3 Participants
Infant Development
Primary: Bayley Composite Scores After 6 Months, Effect Size of Group Difference: COGNITIVE — 111; 111 score on a scale
COVID-19
Primary: Number of Participants With Any Solicited Administration Site Events — 8; 0; 10; 1 Participants
Cannabis Use Disorder
Primary: Number (%) of Participants Who Started and Completed Treatment — 8; 8 Participants
Healthy Adult Subjects
Primary: To Demonstrate the PK Similarity of AVT05 With US Licensed and EU Approved Simponi and the PK of EU Approved Simponi With US Licensed Simponi — 3453.8; 3468.6; 3567.1…
Opioid-use Disorder · Recidivism
Primary: Mean Number of New Eligible Justice Involved Persons Initiated With MOUD Per Month: Intervention Phase — 20.36; 0.55; 4.47; 2.03 New Justice Involved Persons per month…
Lipoprotein Disorder
Primary: Percent Change From Baseline in Time Averaged Lipoprotein(a) [Lp(a)] Over Days 60-180 — -39.0; -74.4; -93.7; 3.1 percent change — p=<0.001