N/A N=336 Talk STEM Familia: Dual-Language (TSFII)
Vocabulary Acquisition
Primary: Student Scientific Academic Vocabulary (SAV) Word Meaning (AVM) — 60.63; 62.43; 65.82; 67.35 percentage of vocabulary words correct — p=.022
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=5 Treating Deep Seizure Foci With Noninvasive Surface Brain Stimulation
Epilepsy, Temporal Lobe
Primary: Self-reported Seizure Frequency — 6.4 seizure days per 4 weeks
Phase 2 N=55 MK-3475 in Combination With MRI-guided Laser Ablation in Recurrent Malignant Gliomas
Malignant Glioma
Primary: Maximum Tolerated Dose (MTD) of MK-3475 When Combined With MLA - Phase I Only — 200 mg
Phase 4 N=16 An Open-label Extension to Assess the Continued Efficacy of Omacor Plus Simvastatin
Dyslipidemias
Primary: Median % Change in Non-HDL-C From Baseline to Week 6 — -51.0; -40.8; -34.9 Median percent change from baseline — p=0.0008
N/A N=32 Imaginal Exposure for Hoarding Disorder
Hoarding Disorder
Primary: Savings Inventory Revised (Frost, Steketee & Grisham, 2004; Tolin, Meunier, Frost & Steketee, 2011) — 62.41; 62.60; 53.41; 52.00 score on a scale
Phase 3 N=532 Multicenter Study in Postmenopausal Women With Osteoporosis, ALVOBOND
Osteoporosis, Postmenopausal
Primary: Percent Change From Baseline in LS BMD at Month 12 to Demonstrate Comparable Efficacy of AVT03 and Prolia®. — 5.3; 5.18 Percent Change From Baseline in LS BMD
Phase 1 N=8 Novel Arm Restraint in the Intensive Care Unit
Acute Respiratory Failure
Primary: Number of Treatment-Emergent Severe Adverse Events [Safety] — 0; 0 number of safety events
Phase 2 N=18 Efficacy of INCMGA00012 in Penile Squamous Cell Carcinoma (ORPHEUS)
Penile Cancer
Primary: Objective Response Rate (ORR) — 3; 15 Participants
Phase 4 N=35 Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment
Endodontic Disease · Post Operative Pain · Symptomatic Irreversible Pulpitis
Primary: Post-operative Pain Level 6 Hours on a Visual Analog Scale — 64.2; 43.1 units on a scale
N/A N=40 The Value of Bio-electrical Impedance Analysis in Irritable Bowel Syndrome
Irritable Bowel Syndrome
Primary: Comparison of the Phase Angle Between IBS Patients and Healthy Individuals — 5.78; 6.35 degrees
Phase 2 N=87 Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy
Pancreatic Cancer · Metastatic Castration-resistant Prostate Cancer · Bladder Cancer
Primary: To Determine the Safety and Tolerability of NGM120 in Subjects — 1; 6; 6; 17 Participants
Phase 2 N=93 A Study to Assess the Safety, Pharmacokinetics and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors
Advanced Solid Tumors
Primary: Percentage of Participants With Treatment-emergent Adverse Events (TEAEs) — 100; 100; 100; 100 percentage of participants
Phase 3 N=100 Randomized Therapy In Status Epilepticus
Status Epilepticus
Primary: Percentage of Participants With SE Cessation Within 30 Minutes of Investigational Product (IP) Initiation Without Medications for the Acute Treatment of SE — 79.59…
N/A N=66 Comparison of Clinical Performance of Two Monthly Replacement Toric Soft Contact Lenses
Ametropia · Astigmatism
Primary: Mean Distance Visual Acuity With Study Lenses at Day 30 — -0.07; -0.06 logMAR
Phase 2 N=8 A 6-Month Extension Study to Assess the Long-Term Safety of Engensis in Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
Primary: Treatment-Emergent Adverse Events in More Than 2 Subjects Overall by System Organ Class and Preferred Term — 3; 3; 0; 2 Participants