17,261 trials
Colorectal Cancer · Colorectal Carcinoma · Colorectal Adenocarcinoma
Primary: Number of Participants With Grade 1-5 Adverse Events — 4; 12; 4; 13 Participants
Urinary Incontinence · Stress · Urination Disorders
Primary: Rate of Product-related, Biopsy Procedure-related, and Injection Procedure-related Adverse Events — 0; 2; 0; 12 events
Acute Leukemia of Ambiguous Lineage · B Acute Lymphoblastic Leukemia · Mixed Phenotype Acute Leukemia
Primary: Tolerability of Azacitidine in Combination With Interfant-06 Standard Chemotherapy in Evaluable Infant Patients With Newly Diagnosed ALL With KMT2A Gene Rearrangement…
Non-small Cell Lung Cancer Stage III
Primary: Grade ≥3 Pneumonitis (CTCAE v4.0) up to 6 Months Post-radiotherapy — 71 Participants
Metastatic Breast Cancer
Primary: Progression-Free Survival (PFS) — 12.3; 14.1; 7.4 months — p=0.227
ALK-positive Advanced NSCLC
Primary: Confirmed Objective Response Rate (ORR) Using RECIST v1.1 as Assessed by the Independent Review Committee (IRC) — 26.2 percentage of participants — p=0.0763
Dry Eye Disease
Primary: Mean Change in Schirmer's Test Score From Baseline to 28 Days — 10.1; 11.7; 11.0; 3.2 score on a scale, mm
Chronic Plaque Psoriasis
Primary: Incidence of Treatment Emergent Adverse Events (TEAEs) Adjusted by Duration of Subject Exposure to Treatment — 110.68; 225.26; 206.82 no. of new events per 100…
Carcinoma, Non-Small-Cell Lung
Primary: Run-in Part: Percentage of Participants With Dose Limiting Toxicities (DLTs) — 1 Participants
Posttraumatic Stress Disorder
Primary: Change in Clinician-Administered PTSD Scale (CAPS-IV) From Baseline to 2-month Follow-up — -55.2; -20.5 score on a scale
Congenital Bleeding Disorder · Haemophilia A With Inhibitors · Haemophilia B With Inhibitors
Primary: The Number of Bleeding Episodes — 47; 77 episodes
Colon Cancer
Primary: Overall Response Rate — 32 percentage of participants
Essential Tremor
Primary: Baseline and Day 28 on The Essential Tremor Rating Assessment Scale Performance Subscale (TETRAS-PS) Total Score — 22.7; 22.8; 21.1; 20.7 score on a scale
Cocaine Use Disorder
Primary: Functional Connectivity Between Corticolimbic Brain Regions During Acute Social Stress — .011; .012; .043; .0008 Arbitrary units
COVID-19
Primary: Mean Cycle Threshold (Ct) Values Through Day 3 as a Measure of Change in Viral Titers of SARS-CoV-2 — 24.36; 26.03; 28.42; 25.71 cycles