65,437 trials
Post-concussive Symptoms · Traumatic Brain Injury
Primary: Post-Intervation Post-concussion Symptom Scores Using RPQ - Intent to Treat — 3.5; 5.1; 4.2; 3.5 units on a scale
Burns · Wound Healing
Primary: Number of Subjects Healed at Day 14. — 35 participants
Cataract
Primary: Deviation From Intended Capsulotomy Diameter — 26.8; 339.1 μm
Gynoid Lipodystrophy
Primary: Mean Change (Decrease) in Cellulite Severity — 2.0; 1.8 units on a scale
Severe Hemophilia B
Primary: Number of Participants With Potentially Clinically Significant Laboratory Abnormalities — 2; 0; 2; 0 participants
Follicular Lymphoma · Small Lymphocytic Lymphoma · Lymphoplasmacytic Lymphoma
Primary: Overall Response Rate — 57.6 percentage of participants — p=< 0.0001
Juvenile Idiopathic Arthritis
Primary: Number of Participants With Treatment-Related Adverse Events of Etanercept — 22 participants
Alzheimer Disease
Primary: Number of Participants With Treatment-Emergent Adverse Events (AEs) or Serious Adverse Events (SAEs) — 5; 3; 6; 3 participants
Bipolar Disorder, Pediatric
Primary: Change From Baseline in Y-MRS Total Score at Day 21 — -9.6; -12.3; -15.1; -15.9 score on a scale — p=0.008
Pulmonary Disease, Chronic Obstructive
Primary: FEV1 AUC0-3h Response at 12 Weeks; Defined as Change From Baseline to Week 12 — 0.313; 0.196 Area Under the Curve (L) — p=<0.0001
Congenital Bleeding Disorder · Haemophilia A
Primary: The Incidence Rate of FVIII Inhibitors (Greater Than or Equal to 0.6 Bethesda Units (BU)) — 0 N with Inhibitors / N with ≥50 EDs
Gaucher Disease, Type 1
Primary: Percentage of Participants Who Remained Stable for 52 Weeks During the Primary Analysis Period — 84.8; 93.6 percentage of participants
Asthma
Primary: Weighted Mean Forced Expiratory Volume in 1 Second (FEV1) Measured Over 24 Hours at Day 14 of Each Treatment Period — 3.303; 3.332; 3.227 Liters
Influenza
Primary: Number of Seroconverted Subjects for Haemagglutination Inhibition (HI) Antibodies Against the A/Turkey/Turkey/1/2005 (A/Turkey) Virus Strain. — 43; 121; 109; 57…
Bipolar Disorder
Primary: Mania Symptoms Using MACS — 18.6; 11.0 units on a scale — p=0.01