65,437 trials
Major Depressive Disorder
Primary: Change in Clinical Global Impression of Severity (CGI-S) for Fatigue Score — -1.5; -1.8; -1.9 units on a scale
Influenza
Primary: Occurrences of Culture- or Polymerase Chain Reaction (PCR)-Confirmed Influenza Caused by Any Influenza Viral Types/Subtypes, in Association With a Protocol-defined…
Insomnia
Primary: Average Wake Time After Sleep Onset (WASO) During the In-Treatment Period — 45.6; 45.5; 76.1 Minutes
Hereditary Angioedema
Primary: Time to Onset of Symptom Relief for an Acute Attack, as Assessed by the Patient — 2.0; 19.8 Hours — p=<0.001
Depression · Major Depressive Disorder · Unipolar Depression
Primary: Montgomery-Asberg Depression Rating Scale (MADRS) — 22.0; 18.0; 12.0; 14.0 units on a scale — p=.04
Colonoscopy · Bowel Preparation · Endoscopy
Primary: Percentage of Subjects With a Successful Preparation (Cleaning Rated as "Good" or "Excellent") — 95; 86 percentage of subjects
Postpartum Depression
Primary: Change in Clinician-rated Montgomery-Asberg Depression Rating Scale (MADRS) — -21.33 units on a scale
Post-operative Nausea · Post-operative Vomiting · Nausea Persistent
Primary: Post-operative Nausea — 24; 70 percentage of subjects with PON
Airway Obstruction · Apnea · Hypopnea
Primary: RI Events in the cNEP Group Compared to the no cNEP Group, Where RI is Defined as Either: i Oxygen Saturation < 90% or ii. Apneas/Hypopneas of > 15 Sec Duration i…
Cigarette Smoking
Primary: 7-day Point-prevalence Smoking Abstinence (6-month) — 69; 53 participants
Lower Urinary Tract Symptoms · Bladder Outlet Obstruction
Primary: Change From Baseline to End of Treatment in Detrusor Pressure at Maximum Flow Rate (PdetQmax) — -1.69; -7.84; -6.69 cmH2O
Diabetes Mellitus, Type 2
Primary: Change in Clearance of Sodium, Potassium, Creatinine, Magnesium, Chloride,Calcium, Phosphate and Uric Acid From Baseline — -0.031; -0.055; -0.071; 0.143 ml/min
Gastroesophageal Reflux Disease
Primary: Percent of Participants Who Experience Each Treatment Emergent Adverse Event Experienced by ≥5% of Participants While Receiving Dexlansoprazole During the 4 Week…
Subjects With an Ileostomy
Primary: Degree of Leakage — 1.8; 1.8; 1.9; 1.7 units on a scale
Colon Cancer · Colorectal Cancer · Rectal Cancer
Primary: Progression-free Survival (PFS) — 10.9; 10.1 months — p=0.3531