65,437 trials
Diabetes · Diabetes Mellitus, Type 2
Primary: Change in Glycosylated Haemoglobin (HbA1c) From Baseline to Week 16 — -1.73; -0.43 percentage of glycosylated haemoglobin — p=<0.0001
Cancer · Head and Neck Cancer · Oncology
Primary: Local Regional Control Rate at 2 Years — 0.51; 0.61 Proportion of Participants
Myopia · Ametropia · Presbyopia
Primary: Subjective Overall Vision — 8.7; 8.4; 8.4; 7.5 Units on a scale
Pain
Primary: Number of Subjects Who Experienced Adverse Events That Led to Study Discontinuation — 1 participants
Lymphoma · Myeloma · Leukemia
Primary: Toxicity — 21; 25 participants
Attention-Deficit/Hyperactivity Disorder
Primary: Change From Baseline in Attention Deficit Hyperactivity Disorder Rating Scale-fourth Edition (ADHD-RS-IV) Total Score at Week 13 — -18.527; -24.552 units on a scale…
Tobacco Use Disorder
Primary: Systolic Blood Pressure Response to Stress — 16.85; 11.71 mmHg — p=<0.001
Arthroplasty, Replacement · Prevention of Venous Thromboembolism · Moderate Renal Impairment (CrCl 30-50 mL/Min)
Primary: Dabigatran Concentration in Plasma, Estimated From Local Hemoclot® — 136 measurements estimated as above LLOQ
Parkinson's Disease
Primary: Unified Parkinson's Disease Rating Score (UPDRS) Part 3 Sum Score — -10.9; -9.5; -4.5 Scores on a scale
Rhinoconjunctivitis · Rhinitis · Conjunctivitis
Primary: The Proportion of Participants Reporting Treatment-emergent Adverse Events (AEs) — 0.446; 0.515; 0.615 Proportion of Participants — p=0.486
Radicular Pain Related to Lumbosacral Disc Disease
Primary: Visual Analogue Scale Score Referring to Radicular Pain (VAS-rad) — 58.7; 67.7; 13.6; 59.7 units on a scale
Generalized Anxiety Disorder (GAD) · Anxiety, Separation · Phobia, Social
Primary: Change From Baseline in Systolic Blood Pressure at Up to 12 Weeks — -1.7; -2.3 mmHg
Paroxysmal Atrial Fibrillation
Primary: Confirmation of Entrance Block in the Pulmonary Veins — 159; 157 participants
Colorectal Cancer · Carcinoma, Neuroendocrine · Neoplasm Metastasis
Primary: Hepatic Progression-free Survival According to Response Evaluation Criterian in Solid Tumors (RECIST) — 3.0; 17.9; 2.9; 3.4 Months
Hypertension
Primary: Mean Change From Baseline in Systolic and Diastolic Blood Pressure (BP) at Week 12 — 151.7; 12.54; 87.6; 8.48 mmHg