65,437 trials
Healthy Participants
Primary: Pharmacokinetics: Area Under the Concentration Curve (AUC) of Testosterone — 2120; 2400; 2970; 2880 nanograms* hours per deciliter (ng*h/dL)
Hot Flashes
Primary: Hot Flash Frequency — 3.48; 3.95; 4.76 Hot flashes per 24 hr
Premature Birth · Brain Injury
Primary: To Find the Dose of Melatonin Required to Achieve Physiological Blood Levels in the Preterm Infants Similar to That of the Mother. — 203.3 pg/ml
Disseminated Neuroblastoma · Recurrent Neuroblastoma
Primary: Median Time to Progression as Assessed by Response Evaluation Criteria in Solid Tumors — 45; 42 days
Overweight · Obesity
Primary: Mean Absolute Change From Baseline to Week 16 in Body Weight - Evaluable Population — -2.68; -3.30; -6.46 kg — p=0.0004
Acute Coronary Syndromes
Primary: The Percentage of Participants With Occurrence of Cardiovascular (CV) Death, Myocardial Infarction (MI), Stroke, Urgent Revascularization (UR), or Glycoprotein (GP)…
Autistic Disorder
Primary: Clinical Global Impression -- Improvement (CGI-I) Scale — 5; 3 participants — p=<.35
Chronic Graft Versus Host Disease
Primary: Overall Response Rate After a 15 Week Course of Bortezomib Plus Prednisone in Patients With cGVHD — 2; 14; 1; 2 participants
Cirrhosis of the Liver
Primary: Perceived HRQoL Score. Overall Qualty of Life Index Tool Was Utilized. — 20.19 scores on a scale
Tobacco Use Disorder
Primary: End of Treatment Abstinence Rate — 19; 18; 19 participants
Plasmodium Falciparum Malaria
Primary: Parasitological Success (MITT) — 66; 28; 4; 43 participants — p=<0.005
Dry Eye Syndromes
Primary: Change in Fluorescein Corneal Staining (FCS) Score From Baseline to Last Observation Carried Forward (LOCF) — -2.8; -3.1; -2.1; -2.6 scores on a scale — p=0.385
Ewing's Sarcoma Family of Tumors
Primary: Objective Response Rate (ORR) — 14.2 percentage of participants
Chronic Obstructive Pulmonary Disease
Primary: Aggregated Pathology Score — 7.88; 8.15 Score on a scale
Hypertension, Pulmonary · Pulmonary Disease, Chronic Obstructive
Primary: Swan-Ganz Hemodynamics - Maximal Change From Baseline at Day 1 of Mean Pulmonary Artery Pressure (PAPmean) — -3.60; -4.83 mmHg