65,437 trials
Advanced Melanoma
Primary: Pharmacokinetic Parameter Maximum Observed Serum Concentration (Cmax) for Ipilimumab, Paclitaxel, Dacarbazine and the Active Metabolite for Dacarbazine…
Adult Acute Megakaryoblastic Leukemia · Adult Acute Monoblastic Leukemia · Adult Acute Monocytic Leukemia
Primary: Complete Remission (CR) Rate — 11 percentage of participants
Type 2 Diabetes · Obesity · Gastric Emptying
Primary: Disposition Index — 703; 532 10^-14dl/kg/min^2 per pmol/l
Soft Tissue Sarcoma
Primary: Overall Response Rate (ORR) — 9; 3; 6 participants
Vascular Disease · Myocardial Ischemia · Coronary Artery Stenosis
Primary: Composite Endpoint of Cardiac Death/TV-MI/CI-TLR (TLF) — 0.00 percentage of participants
Rheumatoid Arthritis
Primary: The Proportion of Participants Meeting the American College of Rheumatology (ACR) Criteria of 20% Improvement (ACR20) After 12 Months of Treatment - Intent to Treat…
Head and Neck Cancer
Primary: Maximum Plasma Concentration of Zalutumumab After Fourth Infusion — 104.3; 258.1; 494.3 mg/L
Myopia · Contact Lenses
Primary: Visual Acuity — -0.056; -0.070; -0.063; -0.065 LogMAR
Colorectal Cancer · Metastases
Primary: Progression-free Survival Time — 8.0; 7.3 weeks — p=<0.0001
Leukemia
Primary: Complete Remission — 52 percentage of participants
Lymphoid Malignancies (New or Relapsed) · Acute Lymphoblastic Leukemia · Burkitt Lymphoma
Primary: Number of Participants With Count Recovery That Allows for Starting a Phase II Study to Evaluate Response Rates and Survival — 7 participants
Age-Related Macular Degeneration
Primary: Mean Change in Visual Acuity From Baseline at the Week 24 Visit — 6.5; 8.8; 10.6 ETDRS Letters
Hypertension
Primary: Change From Baseline (Visit 3) to End of Study (Week 8) in Mean 24 Hour Ambulatory Systolic Blood Pressure (maSBP) — -7.03; -7.79 mmHg
Non Small Cell Lung Cancer
Primary: 1 Year Progression Free Survival — 53.7 percentage of participants — p=0.0645
ANEMIA
Primary: % Patients Achieving Target Hemoglobin Levels — 42.5; 35.3 percentage of participants