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N/A N=7 Randomized Quadruple-blind Basic Science

Vagal Nerve Stimulation and Glucose Metabolism

Type 2 Diabetes · Obesity · Gastric Emptying

Enrolled (actual)
7
Serious AEs
0.0%
Results posted
Jan 2014
Primary outcome: Primary: Disposition Index — 703; 532 10^-14dl/kg/min^2 per pmol/l

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
VNB on (Device); VNB off (Device)
Age
Adult, Older Adult · 35+ yrs
Sex
All
Sponsor
Mayo Clinic
Primary completion
Jun 2012

Outcome Measures

OutcomeResultp-value
PRIMARY
Disposition Index
703; 532
SECONDARY
Gastric Emptying Half-time
167; 160

Summary

The overall aim of this application is to determine the mechanism(s) by which common bariatric surgical procedures alter carbohydrate metabolism. The study proposed will examine the effect of vagal nerve stimulation on insulin secretion and action.

Eligibility Criteria

Previous Implantation of a Vagal Nerve Stimulator for obesity as part of a prior study examining the effect of vagal nerve stimulator on obesity
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01117311). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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