65,437 trials
Chronic Obstructive Pulmonary Disease
Primary: Total Total Transient Dyspnea Index (TDI) Score After 6 Weeks of Treatment QVA149 Compared to Placebo — 7.34; 7.33; 0.98; -0.38 Units on a scale
Psoriasis Vulgaris
Primary: Change in Total Clinical Score From Baseline to Day 22 — -3.6; -3.7; -4.9; -1.3 units on a scale
Short Stature
Primary: Change in Height-for-Age Z-score (HAZ) From End of Supplementation to End of Follow-up Period. — 0.04; -0.08; 0.10; 0.02 Z-Score — p=<0.05
Age-related Macular Degeneration · Cataract
Primary: Development of Advanced AMD in People at Moderate to High Risk for Progression. — 493; 468; 507; 472 Eyes — p=<0.013
Ureteral Stent Occlusion · Exposure Laser · Ureterostomy; Functional Disturbance
Primary: Time to Opening of Eyes — 391.2; 446.5 seconds
Non-small Cell Lung Cancer · Recurrent Non-small Cell Lung Cancer · Stage IIIB Non-small Cell Lung Cancer
Primary: Number of Participants With Objective Response (Complete Response (CR) or Partial Response (PR)) — 1; 12; 17 participants
Chronic Low Back Pain
Primary: Change From Double-blind (DB) Baseline to Final Assessment in Chronic Lower Back Pain (CLBP) Intensity by Visual Analog Scale (VAS) — 1.2; 23.0 scores on a scale
Male Breast Cancer · Recurrent Breast Cancer · Stage IV Breast Cancer
Primary: Fraction of Patients With Increased Levels of Circulating Endothelial Cells — 30 percentage of participants
Adverse Effects
Primary: Pharmacokinetic Parameters Based on Plasma Concentration of Lidocaine and MEGX in Nanograms/Milliliter. — NA; NA nanograms/mililiter — p=<0.05
Malocclusion
Primary: The Rate of Orthodontic Movement of a Maxillary Canine Tooth Being Distalized to Close an Extraction Space. — 0.27; 0.18 mm/week
Chronic Low Back Pain
Primary: Change From Double-blind (DB) Baseline to Final Assessment in Chronic Lower Back Pain (CLBP) Intensity by Visual Analog Scale (VAS) — 1.1; 18.0 scores on a scale
Type 2 Diabetes Mellitus
Primary: Maximum Observed Plasma Concentration (Cmax) of Dapagliflozin From a Single Dose of Dapagliflozin Versus Cmax of Dapagliflozin From Co-administered Saxagliptin Plus…
Obsessive Compulsive Disorder
Primary: Child Yale-Brown Obsessive Compulsive Scale (CY-BOCS) for Adolescents — 26.56; 27.25; 22.44; 19.8 units on a scale
Chronic Low Back Pain
Primary: Change From Double-blind Baseline in Chronic Lower Back Pain (CLBP) Intensity by Visual Analog Scale (VAS) — 10.9; 19.9 scores on a scale
Adenocarcinoma of the Pancreas · Recurrent Pancreatic Cancer · Stage IV Pancreatic Cancer
Primary: Median Overall Survival — 4.7 months