65,437 trials
Melanoma
Primary: Number of Participants Who Completed Treatment — 120 Participants
Type 2 Diabetes Mellitus
Primary: Change From Baseline in HbA1c at Week 12 — -0.20; -0.94 Percent of HbA1c
Multiple Sclerosis · Clinically Isolated Syndrome
Primary: Time to Conversion to Clinically Definite Multiple Sclerosis (CDMS) Defined by Either a Second Attack or a Sustained Increase (Greater Than or Equal to 1.5 Points) in…
Human Immunodeficiency Virus Type 1
Primary: Number of Participants With Virologic Response at Week 48 (Viral Load Less Than 50 Copies Per mL) - as Defined by the Time to Loss of Virologic Response (TLOVR)…
Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome · Acute Myeloid Leukemia/Transient Myeloproliferative Disorder · Adult Acute Myeloid Leukemia in Remission
Primary: Overall Survival — 6; 6 participants
Medical; Abortion, Fetus
Primary: Incidence of Motor Block — 24; 3 participants — p=< 0.001
Intracerebral Hemorrhage · Stroke · Hypertension
Primary: A Composite of Death or Dependency, With Dependency Being Defined by a Score of 3 to 5 on the Modified Rankin Scale (mRS) — 719; 785 participants
Benign Prostatic Hyperplasia
Primary: Change in International Prostate Symptom Scale (IPSS) of Lower Urinary Tract Symptoms From Baseline to 3 Months (Total Score at 3 Months Minus Total Score at Baseline)…
Myelofibrosis With Myeloid Metaplasia · Myeloid Metaplasia · Myelofibrosis
Primary: Percentage of Participants With a Clinical Response Within the First 6 Cycles of Treatment — 55.0; 23.5; 21.1; 47.6 percentage of participants — p=0.092
Gastrointestinal Stromal Tumors
Primary: Progression-free Survival — 147; 28 Days — p=<0.000001
Colorectal Surgery
Primary: To Evaluate Rate of Anastomotic Leaks Related to the Use of the ColonRing™ Device, at 1 Month
Major Depressive Disorder
Primary: Change in Montgomery-Åsberg Depression Rating Scale (MADRS) Total Score — -11.6; -14.8; -15.6; -16.5 Units on a scale — p=0.0186
Obstructive Sleep Apnea
Primary: Comparison of Levels of Mean PAI-1 Activity in Patients With Obstructive Sleep Apnea and Controls. — 17.2; 23.9 IU/ml
Venous Thrombosis
Primary: Adjudicated Composite of Symptomatic, Recurrent Venous Thromboembolism (VTE) or All-Cause Death During the Intended Treatment Period - Randomized Population With…
Major Depressive Disorder
Primary: Change in Montgomery-Asberg Depression Rating Scale (MADRS) Total Score — -14.2; -15.7 units on a scale — p=0.2492