65,437 trials
Irritable Bowel Syndrome
Primary: Colonic Transit Geometric Center at 24 Hours — 3.12; 3.05; 2.77 units on a scale
Pain, Postoperative
Primary: Summed, Time-weighted Pain Intensity Difference From 0 to 24 Hours Postdose (SPID0-24) — 23.2; 23.6; -0.6 Score on the scale
Dry Eye Syndromes
Primary: Changes in Corneal Staining Scores for Study Eye From Baseline at Week 8 — -3.0; -3.0; -3.0; -3.1 Units on a scale
Migraine Disorders
Primary: Subject Self-examination of Skin Irritation — 1.0 scores on a scale
Acute Coronary Syndrome
Primary: Percentage of Participants With a Composite Endpoint of Cardiovascular (CV) Death, Myocardial Infarction (MI), or Stroke — 10.06; 24.64; 10.96; 24.13 percentage of…
Migraine
Primary: Number of Participants With Adverse Events — 110; 85; 79 Participants
Depressive Disorder, Major
Primary: Change From Baseline in the Montgomery-Asberg Depression Rating Scale (MADRS) Total Score at Week 8/Withdrawal — -13.9; -14.4; -12.9 Scores on a scale — p=0.853
Night Eating Syndrome
Primary: Night Eating Questionnaire — -13.0; -10.6 units on a scale
Lennox-Gastaut Syndrome
Primary: Median Percent Reduction in Average Weekly Rate of Drop Seizures Based on the 7-day Assessment — 92.3 percentage of drop seizures
Hepatocellular Carcinoma · Liver Cancer
Primary: Progression-free Survival (PFS) Rate — 64 percentage of participants
Intrauterine Fetal Demise
Primary: Successful Expulsion of Fetus and Placenta Within 48 Hours — 60; 47 participants — p=<0.05
Non-alcoholic Fatty Liver Disease
Primary: Liver Fat Content Change From Baseline to Six Weeks Post H.Pylori Treatment — 2.46; 3.61 percentage of liver fat content
Schizophrenia · Schizoaffective Disorder
Primary: Positive and Negative Syndrome Scale (PANSS) Measuring Symptoms of Schizophrenia — 95; 99; 72; 62 score on scale
Migraine
Primary: Mean Change From Baseline in Monthly Migraine Attacks (According to 24-Hour Rule) Through Month 6 — 5.9; 6.2; 6.6; -0.9 Migraine attacks — p=0.1646
Fragile X Syndrome
Primary: Aberrant Behavior Checklist Irritability Subscore — -5.1; -5.3 Points on a scale — p=0.05