Phase 4 N=15 Iron Indices and Intravenous Ferumoxytol: Time to Steady State
Iron Deficiency Anemia
Primary: Number of Weeks Until Transferrin Saturation (TSAT) and Ferritin Stabilize — 2 weeks
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=150 Effect of Rosiglitazone Versus Placebo on Cardiovascular Performance and Myocardial Triglyceride
Diabetes Mellitus, Type 2
Primary: Peak Oxygen Uptake (VO2) — 26.1; 27.6 ml O2 uptake/kg fat-free mass/minute — p=0.26
Phase 4 N=1,380 Impact Of Smoking Cessation Treatment Reimbursement On The Quit Rates In Smokers Motivated To Quit
Smoking Cessation · Insurance Coverage
Primary: Percentage of Participants With 7-Day Point Prevalence (PP) of Abstinence — 20.8; 13.9 Percentage of Participants — p=0.0007
Phase 4 N=439 Study Evaluating Desvenlafaxine Succinate Sustained-Release (DVS SR) In The Treatment Of Peri- And Postmenopausal Women With Major Depressive Disorder (DVS 3364)
Major Depressive Disorder
Primary: Change From Baseline in Hamilton Depression Scale (HAM-D17) at Week 8 — 22.8; 22.4; -9.7; -7.4 Units on a scale — p=0.004
Phase 4 N=89 Effect of Ferrlecit® Versus Oral Iron on Iron Deficient Chronic Kidney Disease (CKD) Patients
Anemia, Iron-Deficiency · Kidney Failure, Chronic
Primary: Change in Hemoglobin (Hgb) — 0.6; 0.2 g/dL
Phase 4 N=52 Effect of Ferrlecit® Versus Oral Iron on Iron Deficient Chronic Kidney Disease (CKD) Patients Receiving Erythropoietic Agents
Anemia, Iron-Deficiency · Kidney Failure, Chronic
Primary: Baseline Hemoglobin Concentration — 10.3; 10.4 g/dL
Phase 4 N=110 A Re-licensing Study to Assess the Efficacy of Inflexal V Formulated With WHO Recommended 2010/2011 Influenza Virus Strains for the Northern Hemisphere
Influenza
Primary: Seroconversion — 43; 50; 45; 48 Number of subjects
Phase 4 N=30 Effects of Discontinuation of Benzodiazepine-derivative Hypnotics on Cognitive and Motor Functions in Elderly Persons
Adverse Effects
Primary: Completion Rate — 26 percentage of successful completers
Phase 4 N=100 Propofol Versus Ketamine for Moderate Procedural Sedation in the Emergency Department (ED)
Sedation
Primary: Respiratory Depression (Sub-clinical and Clinical Signs) — 0.4; 0.6 percentage of participants
Phase 4 N=41 Effect of Carvedilol Controlled-Release (CR) and Atenolol on Central Blood Pressure
Hypertension
Primary: Central Aortic Blood Pressure — -16.1; -16.0 mmHg
Phase 4 N=81 SERETIDE 100/50 bd (Twice Daily) Versus FLIXOTIDE 100 bd As Initial Maintenance Therapy In Moderate Asthma In Adults
Asthma
Primary: Change From Baseline in Mean Morning Peak Expiratory Flow (PEF) Over Weeks 5-12 — 59.21; 50.98 Liters per minute (L/min) — p=0.683
Phase 4 N=86 Study Evaluating the Effect of Sirolimus on Non-Melanoma Skin Cancer in Kidney Transplant Recipients
Skin Neoplasms · Kidney Transplantation
Primary: New Biopsy-Confirmed Nonmelanoma Skin Cancer (NMSC) Lesions Per Subject Per Year — 1.31; 2.48 Standardized Yearly Rate of NMSC — p=0.022
Phase 4 N=333 Dosing Flexibility Study in Patients With Rheumatoid Arthritis
Rheumatoid Arthritis
Primary: Percentage of ACR20 (American College of Rheumatology 20% Improvement) Responders at Week 34 in Patients Randomized at Week 18 — 65.2; 67.1; 44.9 percentage of subjects
Phase 4 N=335 A Study to Assess the Antibody Response of Healthy Chinese Children Who Have Been Vaccinated Previously With 4-doses of Prevenar (a Pneumococcal Vaccine) as Babies and Toddlers
Pneumococcal Disease
Primary: Geometric Mean Concentration (GMC) for Serotype-specific Pneumococcal Immunoglobulin G (IgG) Antibody, 36 Months After the Toddler Dose — 0.98; 0.66; 0.41; 11.35…
Phase 4 N=109 A Study in Non-squamous Non Small Cell Lung Cancer in Asian Patients
Non Small Cell Lung Cancer
Primary: Progression Free Survival (PFS) During the Induction and Maintenance Therapy Periods — 5.6 months