6,678 trials
Plaque-Type Psoriasis
Primary: At Least a One Grade Improvement for the Target Psoriasis Lesion on the Elbow or Knee (Psoriasis Grading Scale) — 15; 14 participants
Candidiasis
Primary: Number of Participants With Global Response of Success or Failure (Based on Clinical and Microbiological Response) at End of Treatment (EOT) — 170; 33 participants
Major Depressive Disorder
Primary: Change From Baseline in the Apathy Evaluation Scale - Clinician Rated Version (AES-C) Total Score at Week 8 — -13.88; -13.50 units on a scale — p=0.612
Diabetes Mellitus
Primary: Patients With Morning (AM) Glucose Between 80-130 mg/dl on Day 2 and 3 — 10; 18; 14 participants
Sleep Initiation and Maintenance Disorders
Primary: Pain — 3.72; 5.41 scores on a scale
Rheumatoid Arthritis
Primary: Number of Subjects With Low Disease Activity (DAS28 Less Than 3.2) and No Radiographic Progression From Baseline (Change in mTSS Less Than or Equal to 0.5) at Week 78…
Permanent Atrial Fibrillation
Primary: Patients Mode Preference (VRS ON, VRS OFF, NO PREFERENCE) — 32; 32; 15; 15 participants — p=<0.0001
Acute Coronary Syndrome
Primary: Percentage of Participants With Major Adverse Cardiac Events (MACE) (Incidence of MACE) at 30 Days Post-percutaneous Coronary Intervention (PCI) — 14.7; 15.7; 0.6; 0.6…
Diabetes · Diabetes Mellitus, Type 2
Primary: Change in HbA1c From Baseline — -0.48; -0.74 percentage point change
Alcohol Dependence
Primary: Percent of Patients Initiating Vivitrol Treatment Who Receive 3 Consecutive Monthly Vivitrol Injections — 40 Percent of participants
Weaning · Tracheostomy
Primary: Weaning Time — 4.95; 10.15; 4.95; 10.15 day
Constipation
Primary: Patient Preference in Terms of Overall Preference and Preference of Taste, Consistency, and Portability. — 7; 6; 12; 11 participants
Inflammation
Primary: Mean Prostaglandin E2 (PGE2) Aqueous Humor Levels — 1027.4; 1014.7 Picograms per milliliter (pg/ml)
Pulmonary Disease, Chronic Obstructive · Exercise
Primary: 90% Constant Work Rate (CWR) Treadmill Endurance Time at 96 Weeks - Double-Blind Phase — 297.1; 336.6 seconds — p=0.1062
Glaucoma · Ocular Hypertension
Primary: Intraocular Pressure (IOP) at Week 12 — 17.75; 17.90 Millimeters of mercury (mm Hg)