12,372 trials
Pediatric Hypertension With or Without CKD
Primary: Change From Baseline in Mean Systolic Blood Pressure (MSBP) at Week 6 Endpoint — -1.2; -9.2; -6.9; -7.8 mmHg — p=0.0096
Orthotopic Heart Transplant
Primary: Coronary Flow Reserve (CFR) — 1.77 ratio: peak to baseline CFV
Rheumatoid Arthritis
Primary: Percentage of Participants With an American College of Rheumatology 20% (ACR20) Response at Week 12: Period 1 — 68.35; 71.33 percentage of participants
Herpes Zoster
Primary: Anti-glycoprotein E (Anti-gE) Antibody (Ab) Concentrations — 50522.9; 48589.4 mIU/mL
Unresectable or Metastatic Melanoma
Primary: Progression Free Survival (PFS) — 6.87; 11.50; 2.89 months — p=<0.0001
Hepatitis C Virus Infection · Chronic Hepatitis C · Compensated Cirrhosis
Primary: Percentage of Participants With Sustained Virologic Response 12 Weeks Post-treatment (SVR12) — 99.3 percentage of participants
Intracranial Surgery
Primary: Hourly Pain Scores — 2.5; 3.6; 3.7; 5.2 units on a scale
Pregnancy
Primary: Weschler Preschool and Primary Scale of Intelligence, 3rd Edition; Full Scale IQ — 98.78; 98.75 units on a scale
Carcinoid Syndrome
Primary: Number of Participants With Treatment-Emergent Adverse Events (TEAEs) in the Double-Blind Treatment Period — 21; 25; 22 Participants
Major Depressive Disorder
Primary: Number of Participants With Treatment-Emergent Adverse Events (TEAEs) — 562 Participants
Healthy
Primary: Contraception Efficacy of AG200-15 in Subjects ≤ 35 Years of Age Regardless of BMI, Intent-to-treat (ITT) Dataset. — 5.80 Pearl Index
Varicella · Rubella · Mumps
Primary: Number of Subjects Seroconverted for Measles, Mumps, Rubella and Varicella Antibodies — 149; 153; 72; 149 Participants
Influenza
Primary: Number of Seroconverted (SCR) Subjects for Hemagglutination Inhibition (HI) Antibodies Against Flu A/CAL/7/09 H1N1 Virus Strain — 1210; 411; 1012; 301 Participants
Non-Small Cell Lung Cancer
Primary: Progression Free Survival (PFS) by Blinded Independent Review Committee (BIRC) — 16.6; 8.1 Months — p=<0.001
Pharyngitis
Primary: Time Weighted Sum of Pain Intensity Differences (SPID) in Sore Throat Pain Intensity Scale (STPIS) Over the 24 Hours Post-baseline (STPIS SPID24) — -522.9; -326.5 units…