6,678 trials
Scalp Psoriasis
Primary: Number of Participants Who Were a Success or Failure Based on the Global Severity Score (GSS) of Scalp Psoriasis From Baseline to End of Treatment (Week 4 or Week 2 if…
Schizophrenia · Schizoaffective Disorder · Psychotic Disorder
Primary: Mean Number of Drinking Days Per Week — 2.7 Drinking Days per Week
Deep Vein Thrombosis
Primary: Number of Patients With Clinically Relevant Bleeding Events — 32; 32 Patients
Asthma · Coronary Artery Disease · Pulmonary Disease, Chronic Obstructive
Primary: Percentage of Subjects Who Had a >15% Decrease in Forced Expiratory Volume in 1 Second (FEV1) at the 2-hour Postbaseline Assessment — 2.9; 1.1; 5.4; 4.2 Percentage of…
Hypertension
Primary: Pulse Wave Velocity (PWV) Changes From Baseline (Visit 2) to 24 Weeks (Visit 6) After the Administration of the Study Drug — 0.28; -0.12 meters/second
Hypertension
Primary: Change From Baseline to Week 4 in Office Cuff Mean Sitting Systolic Blood Pressure (MSSBP) — 166.2; 164.5; 164.5; 157.5 mm Hg
Fabry Disease
Primary: Number of Participants Experiencing a Clinically Significant Renal, Cardiac or Cerebrovascular Event and/or Death in Fabrazyme (Agalsidase Beta) Patients as Compared to…
Parkinson Disease · Parkinson's Disease
Primary: Mean Change From Baseline in the Japanese Unified Parkinson's Disease Rating Scale (UPDRS) Part III Total Score (in "On" State for the ROP+L-Dopa Group) at Week 52 and…
Psoriasis Vulgaris
Primary: Number of Participants Attaining a 90 Percent Reduction in PASI From Baseline (PASI 90) - ITT — 0; 0; 3; 1 Participants
Pulmonary Disease, Chronic Obstructive
Primary: Mean Change From Baseline in AM (Morning, Approximately 6-9 AM) Pre-dose Forced Expiratory Volume in One Second (FEV1) at Endpoint — 101; -16 milliliters (ml) — p=<0.001
Hypertension
Primary: Change From Baseline to Week 4 in Mean Sitting Systolic Blood Pressure (MSSBP) — 163.9; 163.3; 140.9; 144.4 mmHg
Diabetes · Diabetes Mellitus, Type 2
Primary: Change in Glycosylated Haemoglobin A1c (HbA1c) — -4.450; -4.148 percentage (%) of total haemoglobin
Alcohol Dependence
Primary: Change From Baseline in Blood Oxygen-level-dependent (BOLD) Signal Activation Values Detected in the Reward Circuitry of the Brain in Alcohol-dependent Subjects After…
Hepatitis B, Chronic · Chronic Hepatitis B
Primary: Hepatitis B Virus (HBV) DNA (log10 Copies/mL) Change From Baseline at Week 156 of Adefovir Therapy — 7.94; 3.89; -4.16 log10 copies/mL — p=<0.001
Healthy
Primary: Mean Percent Time That Gastric pH > 4.0 on Day 5 — 36.8; 45.7 percent time gastric pH exceeds 4.0 — p=< 0.0001