12,372 trials
Alcohol Use Disorder
Primary: Change in Heavy Drinking Days Per Week for Dutasteride vs. Placebo Groups — -2.24; -1.41 Heavy Drinking Days per week — p=0.012
Gastroenteritis
Primary: Percentage of Participants With Anti-rotavirus (RV) Immunoglobulin A (IgA) Antibody (Ab) Seroconversion Rate — 88.7; 84.9 Percentage of participants
Influenza, Human
Primary: Percentage of Participants Reporting First Episode of LCI Cases With Associated Per-Protocol ILI Caused by Any Strain at Least 14 Days After Vaccination: 18-64 Years…
Generalized Myasthenia Gravis
Primary: Percentage of Participants With Successful Self-administration of Rozanolixizumab (With Correct Use of Syringe Driver and Manual Push, Respectively) During the…
Abdominal Surgery
Primary: Total Opioids During Postoperative 24 Hours — 26; 33; 31 morphine milligram equivalents — p=0.355
Respiratory Syncytial Virus Infections
Primary: Infants: Percentages of Participants With Medically Significant RSV LRTI With Either Hypoxemia (SpO2 <95% at Sea Level or <92% at Altitudes >1800 Meters) or Tachypnea…
Masseter Muscle Prominence
Primary: Achievement of ≥ 2-Grade Improvement From Baseline on the Masseter Muscle Prominence Scale (MMPS) at Day 90 — 2.2; 51.2 percentage of participants — p=<0.0001
Opioid Toxicity · Pupillary Miosis · Respiratory Depression
Primary: Area Under the Time Concentration Curve (AUROC ) — 0.9700 Probability
Major Depressive Disorder
Primary: Montgomery-Åsberg Depression Rating Scale — -14.7; -9.8 score on a scale — p=<0.0001
Chronic Sinusitis · Chronic Rhinosinusitis (Diagnosis)
Primary: Change From Baseline (CFBL) in the 7-day Average Composite Score of 3 Cardinal Symptoms (3CS) in Participants Without Nasal Polyps. — -2.13; -2.06 score on a scale
Esophageal Cancer · Precancerous Condition
Primary: First Event of Death, Oesophageal Adenocarcinoma, High Grade Dysplasia — 127; 154; 174; 139 Participants — p=0.068
Cervical Adenocarcinoma · Cervical Adenosquamous Carcinoma · Cervical Squamous Cell Carcinoma, Not Otherwise Specified
Primary: Recurrence-free Survival (RFS) Rate at 3-years — 85.4; 88.5 percentage of participants — p=0.0927
Asthma
Primary: Forced Expiratory Volume in 1 Second (FEV1) at the Final Visit (FV) — 2.53; 2.51 Liter
Hemophilia A
Primary: Total Annualized Bleeding Rates (ABR) — 4.1 bleeds per year
Traumatic Brain Injury
Primary: PaO2 — 115; 95 mmHg — p=<0.05