Phase 4 N=111 Travatan Versus Timoptic in Treating Open-angle Glaucoma or Ocular Hypertension
Glaucoma
Primary: Mean Intraocular Pressure (IOP) at 9 AM — 16.3; 18.1 millimeters mercury (mmHg)
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=278 A Study of the Blood Pressure Lowering Ability and Safety of Olmesartan Medoxomil in Stage I and Stage II Hypertension
Hypertension
Primary: Change From Baseline in Mean Systolic Blood Pressure (SBP) After 12 Weeks of Randomized Treatment as Measured by Omron Device. — -0.1; -22.3 mm Hg — p=<0.0001
Phase 4 N=42 The Effect of Ketamine on Interleukin-6 Synthesis in Hepatic Resections Requiring Temporary Porto-arterial Occlusion
Hepatectomy
Primary: The Effect of Ketamine on Interleukin 6 (IL-6) Synthesis in Hepatic Resections Requiring Temporary Porto-arterial Occlusion (Pringle Maneuver) — 116.14; 151.29 pg/ml…
Phase 4 N=66 TRIAGE-CRT Telemonitoring in Patients With CHF and Indication of CRT-D
Congestive Heart Failure · Cardiac Resynchronization Therapy
Primary: Patient Compliance of Weight and Blood Pressure External Monitoring and Home Monitoring Transmissions. Percentage of Days Transmitted. — 71; 71; 83 Percent of days
Phase 4 N=244 Overcome Biochemical Aspirin Resistance Through Cilostazol Combination
Cerebral Infarction
Primary: Aspirin Resistance (ARU ≥ 550) — 9; 11 participants — p=0.654
Phase 4 N=360 Comparator Study Evaluating Patient Experience And Preference Of FFNS vs. FPNS
Rhinitis, Allergic, Perennial
Primary: Comparison of Mean Change From Baseline in Daily Reflective Total Nasal Symptom Score (rTNSS) Over Each Treatment Period of Active Drug Nasal Sprays Versus Placebos…
Phase 4 N=50 Evaluation of Pain With Lidocaine-Mixed Radiesse® Injectable Dermal Filler
Nasolabial Folds
Primary: Pain Score Using a 10-cm Visual Analog Pain Scale (1 = no Pain, 10 = Very Severe Pain) — 2.8; 6.6 cm
Phase 4 N=311 A Randomized, Double-blind, Active (Pramipexole 0.5 mg Tid) and Placebo Controlled, Study of Pramipexole Given 0.5 mg and 0.75 mg Bid Over 12-week Treatment in Early Parkinson's Disease (PD) Patients
Parkinson Disease
Primary: Unified Parkinson's Disease Rating Scale (UPDRS) Total Score — 28.97; 27.66; 27.21; 27.77 units on a scale — p=<0.0001
Phase 4 N=100 The Effect of Anti-inflammatory Analgesics on Pain Following Hallux Valgus Surgery
Postoperative Pain
Primary: Number of Patients Requiring Rescue Medication — 29; 36 patients
Phase 4 N=989 Study of DAPTACEL® Administered as a 5th Dose in 4 to 6-Year-Old Children Previously Immunized With PENTACEL™
Diphtheria · Tetanus · Pertussis
Primary: Percentage of Participants With Solicited Local or Systemic Reactions Post-vaccination With DAPTACEL® as the Fifth Dose After 4 Doses of Pentacel® — 62; 20; 7; 12…
Phase 4 N=99 Perioperative Administration of Pregabalin for Pain After Robot-assisted Endoscopic Thyroidectomy
Pain, Postoperative
Primary: Pain Scores (VNRS) at 1, 6, 24, 48 Hours Postoperatively. — 6; 6; 3; 2 VNRS
Phase 4 N=132 Study to Compare the Safety and Efficacy of Solifenacin With Oxybutynin for the Treatment of Overactive Bladder (VECTOR)
Overactive Bladder
Primary: The Number of Subjects Reporting Incidence of Dry Mouth as an Adverse Event — 24; 53 participants — p=<0.0001
Phase 4 N=70 Tuberculosis and Human Immunodeficiency Virus (HIV) Immune Reconstitution Syndrome Trial (THIRST)
HIV · Tuberculosis
Primary: Number of Serious Adverse Events (SAEs) — 12; 7 Events
Phase 4 N=252 Induction-Maintenance With Atazanavir in HIV Naïve Patients (The INDUMA Study)
HIV Infections
Primary: Percentage of Participants With HIV-1 RNA <50 Copies/mL (c/mL) Through Week 48 of the Maintenance Phase — 78; 75 Percentage of participants
Phase 4 N=480 Comparison of Biphasic Insulin Aspart 30 Versus Insulin Glargine Both in Combination With Metformin and Glimepiride in Subjects With Type 2 Diabetes
Diabetes · Diabetes Mellitus, Type 2
Primary: Glycosylated Haemoglobin A1c (HbA1c) — 7.08; 7.23 percentage of total haemoglobin — p=0.029