Phase 2 N=1,270 COVID-19 Variant Immunologic Landscape Trial (COVAIL Trial)
COVID-19
Primary: Geometric Mean Fold Rise (GMFR) of AUC From Baseline Antibody Against Wa-1 in One Dose Groups. — 4.57; 3.61; 3.78; 3.87 fold rise
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=22 Effects of Niacin Therapy on Lipoprotein Composition and Function
Cardiovascular Disease
Primary: Mean Percent Change in High-density Lipoprotein Protein Concentration — 16.0; -20.0; -15.0; -11.0 Percentage Change
Phase 3 N=513 A 24 Week Trial to Compare the Efficacy and Safety of Delgocitinib Cream 20 mg/g Twice-daily With Alitretinoin Capsules Once-daily in Adult Participants With Severe Chronic Hand Eczema
Chronic Hand Eczema
Primary: Change in HECSI Score From Baseline to Week 12 — -67.6; -51.5 score on a scale — p=<0.001
N/A N=114 Study to Evaluate the Effectiveness, Safety and Long Term Safety of Saypha® FILLER Lidocaine for Lip Augmentation
Abnormal Lip
Primary: Responder Rate in Lip Volume Improvement — 55; 52; 107; 53 Participants
Early Phase 1 N=9 Virtual Reality Exercise in a Community Highschool for Children With Disabilities
Disability Physical · Developmental Disability · Physical Inactivity
Primary: Attendance — 84.4; 31.9 percentage of total sessions attended
N/A N=110 Immersive Multimedia as an Adjunctive Measure for Pain Control in Cancer Patients
Chronic Pain · Cancer
Primary: Change in Visual Analog Scale (VAS) — -9.64; -7.56; -7.91; -8.43 units on a scale
N/A N=7 Automated Medication Platform With Video Observation and Facial Recognition to Improve Adherence to Antiretroviral Therapy in Patients With HIV/AIDS
HIV Infections
Primary: Rate of Medication Adherence — 2; 1 Participants
Phase 1 N=64 Thorough QT/QTc of Pritelivir in Healthy Subjects
Healthy Subjects
Primary: Effects of Pritelivir on the QTcF Interval (QTc Using Fridericia Correction Method) in Comparison With Placebo in Male and Female Subjects. — 402.66; 405.23; 401.94…
N/A N=72 Prospective Study to Investigate the Frequency of Possible Bacterial Entry Into the Bloodstream (Bacteremia) and Infectious Complications Associated With the Use of the Spyglass Cholangioscopy System During ERCP (Endoscopic Retrograde Cholangiopancreatography).
Bile Duct Stricture · Choledocholithiasis
Primary: Number of Patients With Bacteremia — 25; 20; 5; 10 Participants
Phase 4 N=673 A Study of the Effect of Testosterone Replacement Therapy on Blood Pressure in Adult Male Participants With Hypogonadism
Hypogonadism · Hypogonadism, Male · Hypogonadotropic Hypogonadism
Primary: Change From Baseline in 24-Hour Average Systolic Ambulatory Blood Pressure to End of Study (EOS) — 2.77; 2.78; 2.15 millimeters of mercury (mmHg)
Phase 3 N=12 Trial Evaluating Efficacy and Safety of Dasiglucagon in Children With Congenital Hyperinsulinism
Congenital Hyperinsulinism
Primary: Mean Intravenous Glucose Infusion Rate — 4.33; 9.51 mg/kg/minute — p=0.0037
Phase 1 N=21 Safety and Immunogenicity of HIL-214 in Healthy Japanese Infants
Gastroenteritis
Primary: Safety of HIL-214 Compared to Placebo - AEs Leading to Trial Withdrawal — 0; 0 Percentage of Participants
Phase 1 N=17 Single Dose Study of MK-2060 to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Older Japanese Participants on Dialysis (MK-2060-012)
End-Stage Renal Disease (ESRD) · End-Stage Kidney Disease (ESKD) · Kidney Failure, Chronic
Primary: Number of Participants Who Experienced an Adverse Event (AE) — 10; 4 Participants
N/A N=302 Back on Track to Healthy Living Study
Chronic Pain
Primary: Change in Pain Interference (Micro-level Change) — -1.34; -1.03; -0.50; -0.73 scores on a scale — p=>.05
N/A N=100 Heated Humidification System Breathing Circuit for Maintenance of Body Temperature in Pediatric Patients
Temperature Change, Body
Primary: Rectal Temperature — 36.7; 37.2 degrees celsius