65,437 trials
Anterior Cruciate Ligament (ACL) Tear
Primary: Pain Reduction — 1.438; 2.615 Numerical Rating Scale (NRS) — p=0.065123
Electronic Nicotine Delivery System Flavors
Primary: Average Daily Cigarette Use — 10.3; 17.3; 12.3; 5.3 number of cigarettes per day
Resectable Pancreatic Cancer · Unresectable Pancreatic Cancer · Pancreatic Adenocarcinoma
Primary: CA 19-9 Normalization — 40; 13.6; 30; 50 Percentage of participants — p=0.235
Psoriasis · Metabolic Syndrome
Primary: Percentage of Patients Achieving Psoriasis Area and Severity Index (PASI) Score of 90 at Week 28 — 219; 261 Participants — p=0.3857
Cigarette Smoking · Nicotine Vaping
Primary: Proportion of Budget Spent - CIGARETTES — 89.9; 44.5; 87.3; 47.4 percentage of budget spent — p=<0.001
Diabetes Mellitus · Diabetes Mellitus, Type 2 · PreDiabetes
Primary: Change in Diastolic Blood Pressure (mm/Hg) Over a 6-month Period — 6.1; 10.3 mmHg
Colorectal Cancer
Primary: Durable Clinical Benefit — 3; 32 Participants
Transcatheter Aortic Valve Replacement (TAVR)
Primary: Number of Participants With AE /SAE Linked or no Linked With the EasyCross Device — 0 Participants
Non-small Cell Lung Cancer
Primary: Number of Patients With PRO-CTCAE Adverse Events With Score ≥ 3 — 8; 5; 5; 1 participants
Depressive Disorder, Major
Primary: Change in Central Rater Montgomery-Asberg Depression Rating Scale (MADRS) Total Score From Baseline to Post-dose Day 43 — -19.1; -6.8 units on a scale — p=<0.001
Major Depressive Disorder
Primary: HDRS-17 - Hamilton Depression Ratin Scale — 9.41; 7.14 score on a scale — p=0.012
Eye Diseases · Postcataract Aphakia · Cataract
Primary: Mean Residual Manifest Cylinder in Diopters in Toric and Control Arms. — -0.286; -0.813 Diopters — p=<0.0001
Marginal Zone B-cell Lymphoma
Primary: Overall Response Rate — 81.8 Percentage
HIV Infections · Syphilis
Primary: Participants Linked Either to Care (PrEP or ART) — 51; 50 Participants
Asthma
Primary: FEV1 AUC0-12h Normalized by Time on Day 42 (ITT Population) — 2.470; 2.373 liters — p=<0.001