Phase 4 N=129 Non Invasive Mechanical Ventilation in Acute Cardiogenic Pulmonary Edema
Acute Cardiogenic Pulmonary Edema
Primary: Number of Patients Who Were Intubated — 5; 4; 10 participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=388 A Long-Term Safety and Efficacy Study of Eszopiclone in Elderly With Primary Chronic Insomnia
Insomnia
Primary: Mean Change From Baseline in Subject-Reported Total Sleep Time (TST) Averaged Over the 12 Week Double Blind Study Period. — 33.18; 63.24 minutes — p=<0.0001
Phase 4 N=47 A Study Comparing the Withdrawal of Steroids or Tacrolimus in Kidney Transplant Recipients
Kidney Failure · Graft vs Host Disease
Primary: Number of Patients With Biopsy Confirmed Acute Rejection at 12 Months Follow up. — 3; 3; 21; 20 participants — p=1.0
Phase 4 N=875 Study to Monitor the Safety and Reactogenicity of Fluarix™ in Korean Subjects Aged > 6 Months of Age.
Influenza
Primary: Number of Participants Reporting Severe Unsolicited Adverse Events — 0; 0; 0; 0 participants
Phase 4 N=149 Comparing the Effect of Under the Tongue Olanzapine Versus Swallowed Olanzapine on Body Mass Index (A Ratio of Weight to Height)
Schizophrenia · Schizoaffective Disorder · Bipolar Disorder
Primary: Time Course of Change From Baseline in Body Mass Index (BMI) — 0.09; 0.16; 0.25; 0.27 kilograms/square meters — p=0.428
Phase 4 N=100 Effect of Korean Red Ginseng (KRG) on Dry Mouth
Xerostomia
Primary: Visual Analogue Scale of Subjective Dry Mouth — 5.21; 5.03 cm — p=<0.05
Phase 4 N=45 Voriconazole for Secondary Prophylaxis of Invasive Fungal Infections in Patients With Allogeneic Stem Cell Transplants
Prophylaxis Of Invasive Fungal Infections
Primary: Occurrence of Proven or Probable Invasive Fungal Infection (IFI): Start of Prophylaxis Until 12-month Follow-up Visit — 3 participants
Phase 4 N=232 Drug and Non-Drug Treatment Of Severe Migraine
Migraine Headache
Primary: Change in Number of Migraine Episodes Per 30 Days at Month 10. — -2.1; -2.1; -2.2; -3.3 Number of Migraine episodes — p=< .01
Phase 4 N=1,000 A Randomized Study to Compare the Safety and Immunogenicity of Fluviral® Made With New Versus Aged Bulk
Influenza Vaccines
Primary: Geometric Mean Titers (GMTs) of Anti-H3 and B Strains — 369.6; 331.2; 269.6; 245.0 Titer
Phase 4 N=202 A Comparison of Olanzapine in Combination With a Mood Stabilizer vs Mood Stabilizer Alone, in Mixed Bipolar Patients
Bipolar I Disorder
Primary: Mean Change in Young Mania Rating Scale (YMRS) Scores From Baseline to Endpoint. — -10.15; -7.68 units on a scale — p=<0.001
Phase 4 N=300 Long-term Persistence of Immunity Against Hepatitis B in 7-8 Years Old Children After Hepatitis B Vaccination.
Hepatitis B Vaccine
Primary: Number of Participants With Anti-hepatitis B Surface Antigen (HBs) Antibody Concentrations Above the Cut-off Value — 275 Participants
Phase 4 N=79 Study of Two Marketed Ocular Anti-Allergy Medications in Subjects With Allergic Conjunctivitis
Allergic Conjunctivitis
Primary: Change in Ocular Itch Score From Baseline — -1.5; -1.5 units on a scale — p=0.532
Phase 4 N=752 Study Evaluating Etanercept on Skin and Joint Disease in Psoriatic Arthritis
Psoriatic Arthritis
Primary: Number of Patients Achieving "Clear" or "Almost Clear" on Physician Global Assessment (PGA) of Psoriasis — 176; 119 participants
Phase 4 N=41 A Study of Zemplar® Injection and Hectorol® Injection on Intestinal Absorption of Calcium in Chronic Kidney Disease
Chronic Kidney Disease, Stage 5 · Secondary Hyperparathyroidism
Primary: Calcium Absorption Fractions Analyzed by Analysis of Variance (ANOVA) — 0.103; 0.108 Fractions — p=0.573
Phase 4 N=80 Peripheral Body Fat Distribution After Switching Zidovudine and Lamivudine to Truvada
HIV-1
Primary: Change From Baseline in Limb Fat at Week 48 — 392; -257 grams (g) — p=0.0014