12,372 trials
Glabellar Frown Lines
Primary: Facial Wrinkle Scale (FWS) Score of 0 or 1 and an Improvement of ≥ 2 Points in FWS Score (at Maximum Frown) at Week 4 Visit Relative to Baseline, Based on Both the…
Dry Eye · Dry Eye Syndromes
Primary: Conjunctival Redness Assessed Over 90 Minutes in the Dry Eye Chamber — 0.185; 0.156 units on a scale
Glabellar Frown Lines
Primary: Facial Wrinkle Scale (FWS) Score of 0 or 1 and an Improvement of ≥ 2 Points in FWS Score (at Maximum Frown) at Week 4 Visit Relative to Baseline, Based on Both the…
Thrombotic Thrombocytopenic Purpura (TTP)
Primary: Number of Participants With Acute Thrombotic Thrombocytopenic Purpura (TTP) Events During Prophylactic Treatment — 0; 0; 1 Participants
Bipolar Depression · Major Depressive Disorder
Primary: Change From Baseline in Montgomery-Åsberg Depression Rating Scale (MADRS) Total Score — -18.1; -12.4 score on a scale — p=<0.0001
Amyotrophic Lateral Sclerosis
Primary: Change From Baseline in Amyotrophic Lateral Sclerosis Functional Rating Scale - Revised (ALSFRS-R) Score After 48 Weeks. — -11.2; -10.8 units on a scale
Burnout, Caregiver · Burnout, Professional · COVID-19
Primary: Montgomery-Asberg Depression Rating Scale — 21.33; 9.33 score on a scale — p=<.001
Dry Eye
Primary: Schirmer Test Mean Change From Baseline — 1.8; -0.5 length in millimeters
Skin Wound · Burns · Trauma-related Wound
Primary: Percentage of Participants Who Achieved Confirmed Complete Closure of StrataGraft Treatment Sites Without Autograft Within 12 Weeks of StrataGraft Application — 100…
Negative-Pressure Wound Therapy
Primary: Number of Post-op Wound Complications — 2; 5; 42; 36 Wound Complications
Chronic Obstructive Pulmonary Disease
Primary: Annualized Rate of Moderate or Severe Chronic Obstructive Pulmonary Disease (COPD) Exacerbations Over the 52-week Treatment Period — 1.295; 0.859 Exacerbation per…
Adenocarcinoma of Lung
Primary: Objective Response Rate (ORR) During the Induction Study Period From Central Review — 42.40; 42.07 percentage of responders
Gastric Neoplasms · Gastroesophageal Junction Adenocarcinoma
Primary: Progression Free Survival (PFS) Per RECIST 1.1 Assessed by BICR — 10.0; 8.1 Months — p=0.0002
Healthy Volunteers (Meningococcal Infection)
Primary: Percentage of Participants With Serum Bactericidal Assay Using Baby Rabbit Complement (rSBA) Antibody Titers Greater Than or Equal to (>=) 1:8 Against Meningococcal…
Urinary Tract Infections
Primary: Number of Participants With Therapeutic Response (TR) (Combined Per-participant Microbiological and Clinical Success) for Gepotidacin at the Test of Cure (TOC) Visit…