12,372 trials
Actinic Keratoses
Primary: Lesion Response — 89.2; 92.8 percentage of lesions complete response — p=0.0345
Pain, Postoperative
Primary: Total Opiate Requirement — 1.19; 1.01 mg/kg
Alcohol Dependence · Depression
Primary: Number of Drinking Days — 17.6; 12.6 days — p=0.014
Sedentary Lifestyle · Risk of Disability · Aging
Primary: Major Mobility Disability, Defined as Incapacity to Walk 400 Meters — 246; 290 participants — p=0.03
Diabetes Mellitus, Type 2
Primary: HbA1c Change From Baseline After 24 Weeks Double-blind Randomized Treatment — -0.56; -0.65; 0.14 Percentage of HbA1c — p=<0.0001
Hepatitis C, Chronic
Primary: SVR12 Rates With Historical Control — 82.5; 71.6; 72.5; 72.5 Percentage of participants — p=<0.0001
Lysosomal Acid Lipase Deficiency · Wolman Disease
Primary: Percentage Of Participants In The Primary Efficacy Analysis Set (PES) Surviving To 12 Months Of Age — 67 Percentage of participants
Lysosomal Acid Lipase Deficiency
Primary: Percentage Of Participants Achieving Alanine Aminotransferase Normalization — 31; 7; 56; 37 percentage of participants — p=0.0271
Type 2 Diabetes Mellitus
Primary: Percentage of Participants With First Confirmed Cardiovascular (CV) Event of Major Adverse Cardiovascular Event (MACE) Plus (Per Protocol Population) — 9.6; 9.6…
Infertility
Primary: Number of Oocytes Retrieved (Per Protocol Population) — 10.8; 10.6 Number of retrieved oocytes — p=0.0003
Autistic Disorder · Asperger's Disorder · Pervasive Developmental Disorder NOS
Primary: Social Responsiveness Scale (SRS) Change — -13.39; -17.00 units on a scale — p=0.45
Primary Generalized (Osteo)Arthritis · Post-traumatic Arthrosis of Other Joints, Upper Arm
Primary: Device Success Rate — 134 participants
HIV · HIV Infections
Primary: Percentage of Participants With HIV-1 RNA < 50 Copies/mL at Week 48 — 95.6; 92.9; 97.2; 93.1 percentage of participants — p=0.051
Bipolar I Disorder · Bipolar II Disorder · Bipolar Disorder NOS
Primary: Change From Baseline in Digit-Span Score at 8 Weeks — 0.73; 0.17 units on a scale
Complicated Intra-abdominal Infection
Primary: The Proportion of Patients With Clinical Cure at the Test of Cure (TOC) Visit in the Clinically Evaluable (CE) Analysis Set. — 166; 173; 11; 11 Number of patients…