12,372 trials
Rheumatoid Arthritis
Primary: Disease Activity as Measured by Disease Activity Score 28 (DAS28) — 5.4; 3.5; 2.8; 2.2 units on a scale
Breast Cancer · Neoplasm Metastasis
Primary: Progression Free Survival — 7.4; 7.4 Months
Active Polyarticular Juvenile Idiopathic Arthritis
Primary: Abatacept Trough Concentration (Cmin) in Participants Ages 6 to 17 — 39.7 µg/mL
Type 2 Diabetes Mellitus (T2DM)
Primary: Percentage of Patients Who Reported at Least One Symptomatic Hypoglycemic Event During the 24 Week Randomized Period in Both Treatment Arms — 22.2; 45.0 percent of…
Obesity · Premature Recovery From Anesthesia
Primary: Postoperative Care Unit (PACU) Recovery Time — 98.2; 95 Minutes
Heart Failure
Primary: C Reactive Protein — 2.09; 2.93 days
Urinary Incontinence · Multiple Sclerosis · Neurogenic Bladder
Primary: Change From Baseline in Daily Average Frequency of Urinary Incontinence Episodes — 4.18; 4.32; -3.34; -1.10 Episodes
Complicated Intra-abdominal Infections
Primary: Clinical Response of Eravacycline and Ertapenem Treatment Arms at the Test-of-cure (TOC) Visit in the Microbiological Intent-to-treat (Micro-ITT) Population — 191; 198…
Heart Failure, Diastolic · Pulmonary Hypertension
Primary: Mean Pulmonary Artery Pressure Measured by Right Heart Catheterization — -2.4; -4.7 mmHG
Glaucoma
Primary: Intraocular Pressure (IOP) — 16.1; 12.8; 11.7; 11.8 mm Hg
Depression · Depressive Disorder · Depressive Disorder, Major
Primary: Montgomery Asberg Depression Rating Scale — 33.8; 32.6 units on a scale
Squamous Cell Non-small Cell Lung Cancer
Primary: Overall Survival (OS) Time in Months for All Randomized Participants at Primary Endpoint — 9.23; 6.01 months — p=0.0002
Diabetes · Diabetes Mellitus, Type 2
Primary: Change From Baseline in HbA1c (%) Glycosylated Haemoglobin) — -0.54; -0.62; -0.57; -0.59 Percent (%) glycosylated haemoglobin
Parkinson's Disease
Primary: Unified Parkinson's Disease Rating Scale (UPDRS) Total Score — 41.1; 42.9; 34.9; 34.4 units on a scale — p=0.50
Type 2 Diabetes
Primary: Adjusted Mean Change From Baseline in Hemoglobin A1C (HbA1c) at Week 24 — -0.51; -0.16 Percent of glycosylated haemoglobin — p=<0.0001