Phase 2 N=35 Single Dose of pGM169/GL67A in CF Patients
Cystic Fibrosis
Primary: Body Maximum Temperature — 38.6; 38.0; 37.4 celsius — p=0.0002
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=15 A Study Evaluating the Safety and Efficacy of Curcumin in Patients With Primary Sclerosing Cholangitis (PSC)
Primary Sclerosing Cholangitis
Primary: Change in Serum Alkaline Phosphatase (SAP) — 3 Participants — p=.03
Phase 2 N=23 A Study Evaluating the Effects of Ataciguat (HMR1766) on Aortic Valve Calcification
Aortic Valve Stenosis
Primary: Changes in Aortic Valve Calcium Levels — 65; 215 Arbitrary Units — p=0.05
Phase 2 N=36 Phase II, Safety and Efficacy Study of Kamada-alpha-1-antitrypsin (AAT) for Inhalation"
Alpha-1 Antitrypsin Deficiency
Primary: Change From Baseline in the Concentration of Antigenic Alpha-1 Antitrypsin (AAT) in the Lung Epithelial Lining Fluid (ELF) — 4551.023; 13454.772; -27.15 nmol — p=0.0005
Phase 2 N=346 Safety and Immunogenicity of Anti-Pneumococcal Vaccines in HIV-Infected Pregnant Women
PNC Vaccine · HIV-infected Pregnant Women
Primary: Number of Women Who Experienced Various Adverse Events (AEs) — 2; 3; 4; 1 Participants
Phase 2 N=30 Bevacizumab, Capecitabine, and Oxaliplatin in Treating Advanced Small Intestinal or Ampulla of Vater Adenocarcinoma
Ampulla of Vater Adenocarcinoma · Small Intestinal Adenocarcinoma · Stage III Ampulla of Vater Cancer AJCC v8
Primary: Number of Participants With Progression-free Survival (PFS) at Six Months — 68 percentage of participants
Phase 2 N=67 Combination Chemotherapy in Treating Patients With Advanced Stomach, Gastroesophageal, or Esophageal Cancer
Stomach Neoplasms · Esophageal Neoplasms
Primary: Number of Participants With an Objective Response — 25; 22 Participants
Phase 2 N=18 Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled O3 Exposure
Allergic Asthma
Primary: Change From Baseline in Sputum Percent Neutrophils (%PMN) Following Ozone Exposure — 34.1; 36.5 percent neutrophils
Phase 2 N=22 A Phase II Neoadjuvant Study of Apalutamide, Abiraterone Acetate, Prednisone, Degarelix and Indomethacin in Men With Localized Prostate Cancer Pre-prostatectomy
Stage III Prostate Adenocarcinoma AJCC v7 · Stage III Prostate Cancer AJCC v7 · Stage IV Prostate Adenocarcinoma AJCC v7
Primary: Pathologic Complete Response Rate as Assessed From Prostatectomy Specimens Following Neoadjuvant Treatment — 1 Participants
Phase 2 N=30 Adult Study to Evaluate Placement of Tympanostomy Tubes In-office (ADEPT)
Barotrauma;Ear · OME - Otitis Media With Effusion · AOM - Acute Otitis Media
Primary: Subject-reported Pain Score Following Tube Delivery System (TDS) Tube Placement Using the Visual Analogue Scale (VAS) by Subject Compared to a Performance Goal. — 9.4…
Phase 2 N=34 Abraxane in CIMP-High Colorectal and Small Bowel Adenocarcinomas
Colorectal Cancer · Cancer of Gastrointestinal Tract
Primary: Response Rate in CIMP-High Colorectal Cancer and Small Bowel Adenocarcinoma (SBA) — 0; 0; 0; 2 Participants
Phase 2 N=199 Nab-Paclitaxel to Paclitaxel in Advanced Urothelial Cancer Progressing on or After Platinum Containing Regimen.
Urothelial Cancer
Primary: Progression-Free Survival — 3.35; 3.02 Months — p=0.31
Phase 2 N=92 Dose Escalation Study Of Chinese Herbs In Osteoarthritis Of The Knee
Osteoarthritis of the Knee
Primary: ‡Pain Normalized Score — 3.3; 2.7 Units on a scale — p=0.05
Phase 2 N=47 Assessment of Functional Status of Estrogen Receptors in Breast Cancer by Positron Emission Tomography
Breast Cancer
Primary: Change in Primary Tumor FFNP Uptake Before and After Estradiol Challenge as Measured by Percent Change in Standardized Uptake Value (SUV) — 11.0 percent change in SUV
Phase 2 N=16 Apremilast for Atopic Dermatitis - A Pilot Study in Adults
Atopic Dermatitis
Primary: Change in EASI Scores — -8.8; -8.2 units on a scale