65,437 trials
Recurrent Head and Neck Cancer
Primary: Disease-free Survival at 2 Years — 111 Participants
Narcolepsy Type 2
Primary: Change From Baseline in the Average Sleep Latency as Determined From the MWT at Week 8 — 2.14; 1.90; 4.54 minutes — p==0.989
Muscle Strength
Primary: Increased Lower Body Muscle Strength 1/2 — 2410.0; 2492.5 Watts
Crohn Disease · Ulcerative Colitis · Inflammatory Bowel Diseases
Primary: Number of Participants With Clinical Remission for Crohn's Disease — 6 Participants
Atopic Dermatitis
Primary: Number of Participants With Treatment-Emergent Adverse Events — 205; 223; 14; 17 Participants
Narcolepsy Type 1
Primary: Change From Baseline in the Average Sleep Latency as Determined From the MWT at Week 8 — -1.16; 12.49; 23.50; 25.42 minutes — p==0.001
Non-small Cell Lung Cancer
Primary: Percentage of Participants Reporting Quality of Care on Selected National Comprehensive Cancer Center (NCCN) Recommendations — 80; 0; 50; 28.6 percentage of participants
Primary Insomnia
Primary: EEG Power During Sleep — 1.40; 1.17 μV^2/Hz — p=0.2791
Malnutrition
Primary: Experience of the Dietetic Consultation (Number of Participants With Dietetic Consultation Experience That Relate to Each Theme) — 10; 11; 13; 5 Participants
Drug Resistant Epilepsy · Drop Seizures · Generalized Tonic Clonic Seizure
Primary: Part 1: Number of Successful Deployments — 4; 0 number of successful deployments
Neuroendocrine Tumors · Neuroendocrine Neoplasm of Lung
Primary: Clinical Benefit Rate (CBR) — 0; 0; 0; 1 Participants
Symptomatic Neuroma · Morton's Neuroma · Chronic Nerve Pain
Primary: Change in Visual Analog Scale (VAS) For Pain Score at 12 Post-operative Months in Comparative Phase Subjects — -86.62; -72.67 Millimeters (mm) — p=0.011
Healthy Volunteers
Primary: Part 1: Pharmacokinetics (PK): Maximum Observed Plasma Concentration (Cmax) of LOXO-305 — 4000; 4100 nanogram per milliliter (ng/mL)
Asthma · Severe Eosinophilic Asthma
Primary: Proportion of Patients Who Reduced Their Symbicort® Maintenance Dose at the End of the Reduction Period — 0.151; 0.168; 0.605 Proportion of Participants
Hidradenitis Suppurativa
Primary: Percentage of Participants Achieving Clinical Response as Measured by Hidradenitis Suppurativa Clinical Response 50 (HiSCR50) at Week 16 — 28.7; 45.3; 47.8 percentage of…