17,261 trials
Chronic Lymphocytic Leukemia · Prolymphocytic Leukemia · Recurrent Small Lymphocytic Lymphoma
Primary: Overall Survival — 34 Participants
Retinitis Pigmentosa
Primary: Number of Participants With Serious and Non-Serious Adverse Events — 11; 13; 3 Participants
Smoking
Primary: Change From Baseline in True Positives on the 3-Back Level of the Letter-N-Back Neurocognitive Task at Day 28 (i.e., Week 4) — .59; 3.4 True positive responses
Mucopolysaccharidosis I · Hurler Syndrome
Primary: Number of Patients Alive at One Year Post Transplant — 18 Participants
Adolescent Depression
Primary: CDRS-R Score — 34.94; 40.65 score on a scale
Antibody Mediated Rejection of Kidney Transplant
Primary: Renal Allograft Survival Measured by Severe and Refractory Antibody Mediated Renal (AMR) — 1 Participants
Graft Versus Host Disease
Primary: Phase 1b: To Evaluate the Safety and Tolerability of Ibrutinib in Steroid Dependent/Refractory cGVHD. — 0 Participants
Alcohol Drinking
Primary: Number of Drinks Consumed at Lab Session (Day 7) — 4.11; 5.02 drinks
Duchenne Muscular Dystrophy (DMD)
Primary: Change From Baseline in the 6 Minute Walk Test (6MWT) at Week 240 — -199.0; -258.0 Meters
Eosinophilic Esophagitis · Milk Allergy
Primary: Change in Maximum Esophageal Eosinophil Count From Baseline to End of Double-blind Treatment. (Intent to Treat Population) — -10.8; -24.2 Eosinophils (Eos)/high power…
Hypercholesterolemia
Primary: Number of Participants With Adverse Events — 327; 728; 342; 718 Participants
Bronchiectasis
Primary: Number of Participants Reporting Treatment-emergent AEs (TEAEs) up to End of Treatment — 2; 3; 2; 3 Participants
Brain and Central Nervous System Tumors
Primary: (Phase I) Maximum Tolerated Dose (MTD) of Hydroxychloroquine (HCQ) — 3; 7; 3; 0 Participants
Locally Advanced Rectal Cancer
Primary: Pathologic Response at Surgery. Overview of Complete Pathologic Responses, Good and Little Tumour Regression Rates at Surgery. — 34; 11; 41; 24 percentage of cases
Congestive Heart Failure
Primary: PP1- Serum IGF-1 Levels, DXA, Resting Metabolic Rate, Total Body Water, 3-D Echo, Cardiac MRI, Dobutamine Stress Echocardiogram, Ergometry, General Health Assessment…